This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Schulman, D. S. Articles by Wackers, F. J. Search for Related Content PubMed PubMed Citation Articles by Schulman, D. S. Articles by Wackers, F. J.

Hypertension, Vol 10, 16-21, Copyright © 1987 by American Heart Association

ARTICLES

Thallium-201 stress imaging in hypertensive patients

DS Schulman, CK Francis, HR Black and FJ Wackers

To assess the potential effect of hypertension on the results of thallium-201 stress imaging in patients with chest pain, 272 thallium- 201 stress tests performed in 133 hypertensive patients and 139 normotensive patients over a 1-year period were reviewed. Normotensive and hypertensive patients were similar in age, gender distribution, prevalence of cardiac risk factors (tobacco smoking, hyperlipidemia, and diabetes mellitus), medications, and clinical symptoms of coronary disease. Electrocardiographic criteria for left ventricular hypertrophy were present in 16 hypertensive patients. Stepwise probability analysis was used to determine the likelihood of coronary artery disease for each patient. In patients with mid to high likelihood of coronary disease (greater than 25% probability), abnormal thallium-201 stress images were present in 54 of 60 (90%) hypertensive patients compared with 51 of 64 (80%) normotensive patients. However, in 73 patients with a low likelihood of coronary disease (less than or equal to 25% probability), abnormal thallium-201 stress images were present in 21 patients (29%) of the hypertensive group compared with only 5 of 75 (7%) of the normotensive patients (p less than 0.001). These findings suggest that in patients with a mid to high likelihood of coronary artery disease, coexistent hypertension does not affect the results of thallium-201 exercise stress testing. However, in patients with a low likelihood of coronary artery disease, abnormal thallium-201 stress images are obtained more frequently in hypertensive patients than in normotensive patients.

This article has been cited by other articles:

				A Elhendy, R T van Domburg, F B Sozzi, D Poldermans, J J Bax, and J R T C Roelandt Impact of hypertension on the accuracy of exercise stress myocardial perfusion imaging for the diagnosis of coronary artery disease Heart, June 1, 2001; 85(6): 655 - 661. [Abstract] [Full Text]

				M. L. Geleijnse, A. Elhendy, P. M. Fioretti, and J. R. T. C. Roelandt Dobutamine stress myocardial perfusion imaging J. Am. Coll. Cardiol., December 1, 2000; 36(7): 2017 - 2027. [Abstract] [Full Text] [PDF]

				G. Fragasso, C. Lu, P. Dabrowski, P. Pagnotta, I. Sheiban, and S. L. Chierchia Comparison of stress/rest myocardial perfusion tomography, dipyridamole and dobutamine stress echocardiography for the detection of coronary disease in hypertensive patients with chest pain and positive exercise test J. Am. Coll. Cardiol., August 1, 1999; 34(2): 441 - 447. [Abstract] [Full Text] [PDF]

				L. Cortigiani, E. A. Paolini, and E. Nannini Dipyridamole Stress Echocardiography for Risk Stratification in Hypertensive Patients With Chest Pain Circulation, December 22, 1998; 98(25): 2855 - 2859. [Abstract] [Full Text] [PDF]

				A. Elhendy, R. T. van Domburg, J. R. T. C. Roelandt, M. L. Geleijnse, M. M. Ibrahim, and P. M. Fioretti Safety and Feasibility of Dobutamine-Atropine Stress Testing in Hypertensive Patients Hypertension, June 1, 1997; 29(6): 1232 - 1239. [Abstract] [Full Text]

				M. P. Cecil, W. A. Fajman, J. A. Ziffer, and E. D. Frohlich The Heart in Hypertension N. Engl. J. Med., January 21, 1993; 328(3): 212 - 213. [Full Text]

				J. S. Gottdiener, J. Brown, J. Zoltick, and R. D. Fletcher Left Ventricular Hypertrophy in Men with Normal Blood Pressure: Relation to Exaggerated Blood Pressure Response to Exercise Ann Intern Med, February 1, 1990; 112(3): 161 - 166. [Abstract] [PDF]