Hypertension, Vol 11, 545-549, Copyright © 1988 by American Heart Association
GD James, TG Pickering, LS Yee, GA Harshfield, S Riva and JH Laragh
The reproducibility of ambulatory, home, and clinic blood pressures was
compared in 13 untreated mildly hypertensive and 14 normotensive subjects.
Each subject had two sets of daily ambulatory recordings, home
self-measured readings (over 6 days), and clinic measurements taken 2 weeks
apart. Comparisons over the 2 weeks within and among the methods of
measurements were made using a repeated-measures analysis of variance. The
results showed that there was no consistent average change in the
ambulatory or home pressures and no change in clinic diastolic pressures,
but the clinic systolic pressure of the hypertensive subjects dropped 6 mm
Hg (p less than 0.05), while that of the normotensive subjects showed no
significant change. Test-retest correlations of each of the three methods
were similar in magnitude, indicating a similar level of reliability.
Test-retest correlations of the ambulatory standard deviations, however,
were low, indicating a low reliability of this measure of daily pressure
variability. These results suggest that the reproducibility of ambulatory
pressures may be as good or better than that of home or clinic
measurements. They also suggest that the average ambulatory pressure may be
preferable as the measurement in clinical trials, since it may be less
influenced by measurement anxiety, particularly in hypertensive subjects.
ARTICLES
The reproducibility of average ambulatory, home, and clinic pressures
Cardiovascular Center, Cornell University Medical College, New York Hospital, NY 10021.
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