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Hypertension, Vol 13, 38-42, Copyright © 1989 by American Heart Association

ARTICLES

Comparison of variability of urinary sodium, potassium, and calcium in free-living men

A Siani, L Iacoviello, N Giorgione, R Iacone and P Strazzullo
Institute of Internal Medicine and Metabolic Disease, 2nd Medical School, University of Naples, Italy.

The variability of 24-hour urinary sodium, potassium, and calcium excretion was studied in a sample of 22 Neapolitan men with mild blood pressure elevation. On 5 days within a 1-month period, 24-hour urine specimens were collected by each subject. The estimated ratio of intraindividual-to-interindividual variance was 1.12 for urinary sodium, 2.46 for urinary potassium, and 0.52 for urinary calcium. Based on these values, five 24-hour urine collections are necessary to reduce to less than 10% the diminution of the correlation coefficient between urinary sodium and another related variable; this number is substantially lower than that found in previous studies in a North American population sample, but similar to the one reported for Chinese population samples. Ten urinary collections are needed for potassium excretion. A different and more favorable situation is observed for 24- hour calcium excretion, as only two collections are necessary for the adequate characterization of individuals in a population.

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