Hypertension, Vol 17, 707-719, Copyright © 1991 by American Heart Association
M Martinez-Maldonado
Renovascular hypertension has its experimental counterpart in the two-
kidney, one clip model (Goldblatt hypertension). From the study of this
model, a general pathophysiological scheme has evolved suggesting that
temporal stages in the development and maintenance of hypertension are
regulated by complicated hormonal and neural interrelations. The central
roles played by the renin-angiotensin system and the renal nerves is
discussed as they relate to other hormones. In addition, the possible
contribution of converting enzyme inhibitors to understanding the
pathophysiology of this condition is discussed.
ARTICLES
Pathophysiology of renovascular hypertension
Atlanta Department of Veterans Affairs Medical Center, Decatur, GA 30033.
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