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Hypertension, Vol 22, 630-633, Copyright © 1993 by American Heart Association

ARTICLES

Transgenesis in nonmurine species

JJ Mullins and LJ Mullins
AFRC Centre for Genome Research, University of Edinburgh, UK.

Although the mouse remains the species of choice for most transgenic experimentation, it may be preferable or even necessary to use alternative species for certain applications. We review the strategies by which transgenic technology has been applied to other animals, specifically, the rat, rabbit, pig, sheep, goat, and cow. Additionally, we outline the potential applications of alternative transgenic species with reference to the field of hypertension and cardiovascular research.

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