(Hypertension. 1997;30:782-787.)
© 1997 American Heart Association, Inc.
Articles |
Cardiovascular Reactivity to Stress and Left Ventricular Mass in Youth
From the Department of Psychiatry (M.T.A., K.A.M.) and Departments of Pediatrics and Obstetrics, Gynecology, and Reproductive Sciences (F.S.S.), University of Pittsburgh (Pa).
Abstract We studied the relationships of
cardiovascular reactivity during mental stress with
left ventricular mass index in a group of prepubertal
children 8 to 10 years old and in a group of peripubertal or
postpubertal adolescents 15 to 17 years old. One hundred fifteen
participants, varying in age group, sex, and race (black and white),
took part in a laboratory stress protocol consisting of a reaction-time
task, a mirror tracing task, a cold forehead challenge, and a stress
interview. Cardiovascular measures included blood
pressure and heart rate, as well as cardiac output, stroke volume,
total peripheral resistance, and preejection period
obtained noninvasively with impedance cardiography. Measures of left
ventricular mass were made by
echocardiography. Results indicated that across all
participants, left ventricular mass index was associated
with cardiovascular responses during the mirror tracing
and cold forehead tasks, especially with those responses reflecting
increased vasoconstriction. Subgroup analyses showed that these
associations were significant for males and sometimes adolescents but
not for females and children. As mirror tracing and cold forehead tasks
most consistently produce 
-adrenergic activation, the
results suggest a model in which vasoconstriction due to mental stress
is related to increased left ventricular mass in
susceptible individuals, even at a young age.
Key Words: left ventricular mass • cardiovascular reactivity • children • adolescents • stress • ethnicity
This article has been cited by other articles:
 |
|
 |
|
  A. Jones, A. Beda, C. Osmond, K. M. Godfrey, D. M. Simpson, and D. I.W. Phillips Sex-specific programming of cardiovascular physiology in children Eur. Heart J., September 1, 2008; 29(17): 2164 - 2170. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Carroll, A. C. Phillips, and G. Der Body Mass Index, Abdominal Adiposity, Obesity, and Cardiovascular Reactions to Psychological Stress in a Large Community Sample Psychosom Med, July 1, 2008; 70(6): 653 - 660. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. I. W. Phillips and A. Jones Fetal programming of autonomic and HPA function: do people who were small babies have enhanced stress responses? J. Physiol., April 1, 2006; 572(1): 45 - 50. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Carroll, C. Ring, K. Hunt, G. Ford, and S. Macintyre Blood Pressure Reactions to Stress and the Prediction of Future Blood Pressure: Effects of Sex, Age, and Socioeconomic Position Psychosom Med, November 1, 2003; 65(6): 1058 - 1064. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Sherwood, E. C. D. Gullette, A. L. Hinderliter, A. Georgiades, M. Babyak, R. A. Waugh, and J. A. Blumenthal Relationship of Clinic, Ambulatory, and Laboratory Stress Blood Pressure to Left Ventricular Mass in Overweight Men and Women With High Blood Pressure Psychosom Med, March 1, 2002; 64(2): 247 - 257. [Abstract] [Full Text]
|
|
|
|
|
|
D. Carroll, G. D. Smith, M. J. Shipley, A. Steptoe, E. J. Brunner, and M. G. Marmot Blood Pressure Reactions to Acute Psychological Stress and Future Blood Pressure Status: A 10-Year Follow-Up of Men in the Whitehall II Study Psychosom Med, September 1, 2001; 63(5): 737 - 743. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Andre-Petersson, G. Engstrom, B. Hagberg, L. Janzon, G. Steen, D. A. Lane, D. Carroll, and G. Y.H. Lip Adaptive Behavior in Stressful Situations and Stroke Incidence in Hypertensive Men: Results From Prospective Cohort Study "Men Born in 1914" in Malmo, Sweden Editorial Comment: Results From Prospective Cohort Study "Men Born in 1914" in Malmo, Sweden Stroke, August 1, 2001; 32(8): 1712 - 1720. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. W. Kamarck, J. Eranen, J. R. Jennings, S. B. Manuck, S. A. Everson, G. A. Kaplan, and J. T. Salonen Anticipatory Blood Pressure Responses to Exercise Are Associated With Left Ventricular Mass in Finnish Men : Kuopio Ischemic Heart Disease Risk Factor Study Circulation, September 19, 2000; 102(12): 1394 - 1399. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. K. Kapuku, F. A. Treiber, H. C. Davis, G. A. Harshfield, B. B. Cook, and G. A. Mensah Hemodynamic Function at Rest, During Acute Stress, and in the Field : Predictors of Cardiac Structure and Function 2 Years Later in Youth Hypertension, November 1, 1999; 34(5): 1026 - 1031. [Abstract] [Full Text] [PDF]
|
|