From the Center for Health Promotion, (L.R.Y., T.F.M., J.V.R., R.M.Y.,
D.M.B.); the Division of Cardiology (R.S.B., L.C.B.); and the School of
Nursing (M.N.H.), The Johns Hopkins Medical Institutions, Baltimore, Md.
Abstract—To determine the extent to
which the Fifth Joint National Committee on Detection, Evaluation, and
Treatment of High Blood Pressure (JNC-V) guidelines were implemented in
high-risk families with premature coronary heart disease, we
examined the prevalence of hypertension and associated coronary
risk factors in asymptomatic siblings of persons with
documented premature coronary disease (<60 years of age). A
total of 859 apparently healthy siblings (51% male, 19% African
American) were screened for coronary risk factors. Siblings
were classified as normotensive or hypertensive (BP
© 1998 American Heart Association, Inc.
Scientific Contributions
Hypertension Among Siblings of Persons With Premature Coronary Heart Disease
140/90 and/or
current antihypertensive pharmacotherapy). The prevalence of
hypertension, awareness, treatment, and control among siblings was
compared with published national estimates from the third National
Health and Nutrition Examination Survey. The prevalence of hypertension
in siblings was 44%. Among all hypertensives, only 60% were aware of
being hypertensive, 45% were being treated, and 16% were under
control. A high prevalence of other coronary risk factors was
found among hypertensive siblings: 72% were
hypercholesterolemic; 61% were obese; 29% were
current smokers; 82% were consuming >30% of calories from fat; and
only 14% were participating in vigorous physical activity three or
more times per week. Comparisons with the national reference population
revealed siblings to have a significantly higher prevalence of
hypertension, along with significantly lower levels of awareness,
treatment, and control. These findings demonstrate the intersection of
multiple risk factors among hypertensive siblings and emphasize the
need for more aggressive screening and treatment in this easily
identifiable high-risk population.
Key Words: blood pressure • prevalence • hypertension, detection and control • risk factors • family
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