Hypertension, Vol 5, 746-748, Copyright © 1983 by American Heart Association
J Conway, N Boon, JV Jones and P Sleight
We have measured baroreflex sensitivity and blood pressure in 13 subjects
during sleep and three stages of progressive mental arousal after waking.
Baroreflex sensitivity was measured by correlating the increase in pulse
interval with the increase in systolic pressure produced by an intravenous
injection of 80 micrograms of phenylephrine. Blood pressure was measured
directly from the brachial artery. During sleep, blood pressure fell and
baroreflex sensitivity increased; with increasing mental arousal, blood
pressure rose and baroreflex sensitivity decreased. These results suggest
that baroreflex activity may be involved in the medium-term regulation of
blood pressure during the day and night in addition to its recognized role
in buffering acute changes in blood pressure.
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Involvement of the baroreceptor reflexes in the changes in blood pressure with sleep and mental arousal
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