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Hypertension. 1984;6:281-284

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Hypertension, Vol 6, 281-284, Copyright © 1984 by American Heart Association


ARTICLES

Rapid cyclic fluctuations of blood pressure associated with an adrenal pheochromocytoma

A Ganguly, CE Grim, MH Weinberger and DP Henry

We present a patient with an adrenal pheochromocytoma with an unusual pattern of periodic alternating hypertension and hypotension. Alpha- adrenergic blockade alone failed to affect this pattern, which was abolished only after fluid repletion. The efficacy of volume expansion in ultimately correcting the wide fluctuations of blood pressure implicates a possible reflex neurogenic mechanism for the cyclic changes in blood pressure attributable to intravascular volume contraction.