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Hypertension, Vol 6, 731-735, Copyright © 1984 by American Heart Association

ARTICLES

Effect of dietary sodium reduction on red blood cell sodium concentration and sodium-lithium countertransport

R Cooper, M Trevisan, L Van Horn, E Larbi, K Liu, S Nanas, H Ueshima, C Sempos, D Ostrow and J Stamler

A randomized, crossover trial was carried out on the effect of moderate sodium reduction on red-blood-cell sodium metabolism. The participants were healthy high school students (mean age = 16 years, n = 33). Changes in sodium-lithium countertransport and intracellular sodium concentration were evaluated 24 days after a decrease in dietary sodium from approximately 110 to 40 mEq per day. Dietary sodium restriction had no significant effect on either sodium-lithium countertransport or intracellular sodium concentration.

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