| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Hypertension. 2006;47:325.)
© 2006 American Heart Association, Inc.
Editorial Commentaries |
From the Department of Pharmacology and Inserm, Hôpital Européen Georges Pompidou, Paris, France.
Correspondence to Stéphane Laurent, Department of Pharmacology and Inserm EMI 0107, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France. E-mail stephane.laurent@egp.ap-hop-paris.fr
An extract of the first 250 words of the full text is provided, because this article has no abstract. |
Recent epidemiological studies have shown that arterial stiffness, measured through carotid-femoral pulse wave velocity (PWV), has an independent predictive value for cardiovascular (CV) events in several populations, including patients with uncomplicated essential hypertension1,2 and type 2 diabetes.3 Arterial stiffness is thus an intermediate end point for CV events, predicting CV events independently of and beyond peripheral pulse pressure (PP).
Peripheral PP, central PP, and augmentation index, which provide additional information on wave reflection, are considered "surrogates" of arterial stiffness, because their pathophysiological meaning is clearly different.46 Central PP and augmentation index are dependent on the speed of wave travel, the amplitude of reflected wave, the reflectance point, and the duration and pattern of ventricular ejection, especially with respect to change in heart rate and ventricular contractility. Aortic PWV, which is the speed of wave travel, represents intrinsically arterial stiffness, according to the Bramwell-Hill formula.46
Two articles7,8 in the present issue of Hypertension raise the issue of the predictive value of "surrogates of arterial stiffness" for CV events. Li et al7 studied the dynamic relationship between diastolic blood pressure (DBP0 and systolic blood pressure (SBP) in ambulatory blood pressure monitoring (ABPM) data throughout the day and calculated a novel index as 1 the regression slope of DBP on SBP. This index was named ambulatory arterial stiffness index (AASI) on the basis that "average distending BP varies during the day, and that the relation between DBP and SBP with this changing distending BP largely depends on the structural and functional characteristics of
Related Articles:
Hypertension 2006 47: 359-364.
Hypertension 2006 47: 365-370.
This article has been cited by other articles:
![]() |
A. N. Gurovich, D. T. Beck, and R. W. Braith Aortic Pulse Wave Analysis Is Not a Surrogate for Central Arterial Pulse Wave Velocity Experimental Biology and Medicine, November 1, 2009; 234(11): 1339 - 1344. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. D. Cameron Wave Intensity Analysis and Central Blood Pressure Hypertension, November 1, 2009; 54(5): 958 - 959. [Full Text] [PDF] |
||||
![]() |
A. Adiyaman, D. G. Dechering, J. Boggia, Y. Li, T. W. Hansen, M. Kikuya, K. Bjorklund-Bodegard, T. Richart, L. Thijs, C. Torp-Pedersen, et al. Determinants of the Ambulatory Arterial Stiffness Index in 7604 Subjects From 6 Populations Hypertension, December 1, 2008; 52(6): 1038 - 1044. [Abstract] [Full Text] [PDF] |
||||
![]() |
R Schutte, T Nawrot, T Richart, L Thijs, H A Roels, L M Van Bortel, H Struijker-Boudier, and J A Staessen Arterial structure and function and environmental exposure to cadmium Occup. Environ. Med., June 1, 2008; 65(6): 412 - 419. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Schillaci, G. Parati, M. Pirro, G. Pucci, M. R. Mannarino, L. Sperandini, and E. Mannarino Ambulatory Arterial Stiffness Index Is Not a Specific Marker of Reduced Arterial Compliance Hypertension, May 1, 2007; 49(5): 986 - 991. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Westerhof, J.-W. Lankhaar, and B. E. Westerhof Letter to the Editor: Ambulatory Arterial Stiffness Index Is Not a Stiffness Parameter But a Ventriculo-Arterial Coupling Factor Hypertension, February 1, 2007; 49(2): e7 - e7. [Full Text] [PDF] |
||||
![]() |
B. Williams The Year in Hypertension J. Am. Coll. Cardiol., October 17, 2006; 48(8): 1698 - 1711. [Full Text] [PDF] |
||||
![]() |
E. O'Brien Ambulatory Blood Pressure Measurement: A Trove of Hidden Gems? Hypertension, September 1, 2006; 48(3): 364 - 365. [Full Text] [PDF] |
||||
|
Hypertension Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search Copyright © 2006 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. |