Published online before print June 12, 2006, doi: 10.1161/01.HYP.0000226411.97252.e6
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(Hypertension. 2006;48:21.)
© 2006 American Heart Association, Inc.
Editorial Commentary |
Adiposity in Youth and Blood Pressure
From the Medical University South Carolina, Charleston.
Correspondence to Peter W.F. Wilson, Medical University South Carolina, 96 Jonathan Lucas St, Suite 815 Charleston, SC 29425. E-mail wilsonpw@musc.edu
An extract of the first 250 words of the full text is provided, because this article has no abstract. |
The metabolic syndrome is a constellation of several traits that often coexist and augment risk for atherosclerotic disease, diabetes mellitus, and other conditions. The article by Srinivasan et al1 in this issue of Hypertension reports on changes in blood pressure over time in persons according to metabolic syndrome trait status, and the authors focus on issues related to adiposity. They highlight the longitudinal blood pressure experience of the Bogalusa Study in pediatric, adolescent, and adult age groups. The authors conclude that higher prehypertension is likely to be accompanied by increased adiposity; other metabolic abnormalities, such as elevated triglycerides, higher low-density lipoprotein cholesterol, and higher insulin levels accompany frank hypertension.
Previous research has shown that weight gain in the Framingham Offspring population sample was a key contributor to the development of increasing systolic and diastolic pressure and the occurrence of hypertension over an 8-year follow-up interval.2 A later Framingham Offspring study with 16 years of follow-up showed that greater adiposity at baseline and weight change were both highly related to the degree of metabolic risk factor clustering.3 The mean number of metabolic factors increased significantly in those who gained >5 pounds over the study interval compared with persons whose weight remained stable. The Framingham analysis was largely based on the experience of a white middle-aged population group, and the current article by Srinivasan et al1 finds similar relationships in younger individuals and includes blacks.
The top of Table 4 in the article by Srinivasan et al1 provides a strong and simple
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Hypertension 2006 48: 33-39.