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(Hypertension. 1997;29:b4.)
© 1997 American Heart Association, Inc.

Awards

CIBA Award for Hypertension Research 1996

In recognition of outstanding contributions made in hypertension research, the CIBA Award has been presented at the annual meeting of the Council for High Blood Pressure Research since 1975. The CIBA Award continues the tradition of the Stouffer Prize, first awarded to Ernst Klenk, MD, and Harry Goldblatt, MD, in 1966. In 1996 the CIBA Award was presented to two recipients.

View larger version (129K): [in this window] [in a new window]   Robert J. Lefkowltz. MD

Dr Lefkowitz received the CIBA Award for his seminal research that led to the discovery of the nature, mechanism of action, and means of regulation of the adrenergic and other G protein-coupled receptors, which regulate the cardiovascular system and control blood pressure.

Dr Lefkowitz was born in New York City where he obtained his BA and MD degrees from Columbia University. After 2 years of housestaff training at Columbia Presbyterian Medical Center, he spent 2 years at the NIH and then 3 years pursuing further clinical and research training at the Massachusetts General Hospital in Boston before taking up a position as Associate Professor of Medicine at Duke University in 1973. He was appointed an Investigator of the Howard Hughes Medical Institute in 1976 and named James B. Duke Professor of Medicine in 1982—positions he has held until the present.

Dr Lefkowitz’s entire research career, spanning almost 30 years, has been devoted to the study of receptors. He pioneered the development of ligand binding approaches, methods for receptor purification, cloning of their genes, and elucidation of the structural basis for their function. He also elucidated the mechanisms that regulate receptor function through desensitization. His research has contributed to the development of a variety of drugs to treat heart disease and hypertension.

Dr Lefkowitz has been elected to several prestigious societies, including the USA National Academy of Sciences (NAS), the NAS’s Institute of Medicine, and the American Academy of Arts and Sciences. He has received numerous awards for his research including the Gairdner Foundation International Award, the Passano Award, and the BristolMyers Squibb Award for Distinguished Achievement in Cardiovascular Research.

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