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(Hypertension. 2007;50:e8.)
© 2007 American Heart Association, Inc.

Letters to the Editor

Response to Polycystic Ovary Syndrome: Androgens, Autonomic Nervous System, and Hypertension

Departments of Obstetrics and Gynecology, National Taiwan University Hospital, and Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

Lian-Yu Lin

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

Yu-Shih Yang

Departments of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan

We thank Dr Perciaccante¹ and his colleague for their interest and insightful comments on our recent article² regarding the association between the characteristic hyperandrogenemia and the elevated systolic and diastolic blood pressure in young women with polycystic ovary syndrome.

Perciaccante et al propose that the cardiovascular autonomic nervous system might be affected directly by androgen levels or by hyperandrogenemia-induced insulin resistance and might, therefore, act as a possible link between androgen and blood pressure in women with polycystic ovary syndrome. We agree entirely that the mechanisms underlying hyperandrogenemia and elevated blood pressure are complex, and impaired autonomic nervous system might be a possible reason to explain this association.

However, further investigation and controlled studies are still necessary to substantiate this hypothesis.

	Acknowledgments

 
Sources of Funding

This study was supported by grants NSC94-2314-B002-195 and NSC95-2314-B002-035 from the National Science Council of Taiwan.

Disclosures

None.

	References

Top References

 
1. Perciaccante A, Fiorentini A, Valente R, Tubani L. Polycystic ovary syndrome: androgens, autonomic nervous system, and hypertension. Hypertension. 2007: 50: e7.[Free Full Text]

2. Chen M-J, Yang W-S, Yang J-H, Chen C-L, Ho H-N, Yang Y-S. Relationship between androgen levels and blood pressure in young women with polycystic ovary syndrome. Hypertension. 2007: 49: 1442–1447.[Abstract/Free Full Text]

This Article Extract Full Text (PDF) All Versions of this Article: 50/1/e8    most recent HYPERTENSIONAHA.107.091801v1 Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Chen, M.-J. Articles by Yang, Y.-S. Search for Related Content PubMed PubMed Citation Articles by Chen, M.-J. Articles by Yang, Y.-S. Related Collections Glucose intolerance Clinical Studies