Hypertension, Vol 13, 22-30, Copyright © 1989 by American Heart Association
SH Lai, YC Tang, WL He, PS Mo and GQ He
The relation between blood pressure and urinary electrolytes, including
sodium, potassium, calcium, and magnesium were examined in male farmers of
the Yi nationality who live in three separate communities in Sichuan and
Yunnan provinces in China, where the lifestyles, habits, and living
conditions are very different. One of these three communities was
unacculturated and had the lowest average blood pressure as well as the
lowest prevalence rate of hypertension in China; one was acculturated and
had the highest average blood pressure; and the third was moderately
acculturated with its average blood pressure between the other two. Blood
pressure was taken on each of 3 days and corresponding 24-hour urine
specimens were collected to measure potassium, sodium, calcium, magnesium,
urea nitrogen, and creatinine. Ecological and individual-based data
correlation analyses were employed to study the relations among age, body
mass index, some related indexes of electrolyte derivatives, and blood
pressure. Multiple regression analyses were used to explore the relation of
blood pressure to the above indexes, adjusted for age, body mass index,
urea nitrogen and creatinine, and geographical differences. Statistically
significant correlation analyses showed that systolic blood pressure was
positively associated with sodium-creatinine, calcium-creatinine, sodium-
potassium, calcium-magnesium, and urea nitrogen and creatinine ratios;
negatively associated with potassium-creatinine and magnesium- creatinine
ratios. The ridge regression analysis selected only calcium- magnesium
ratio as a predictor of systolic blood pressure.
ARTICLES
Urinary electrolytes and blood pressure in three Yi farmer populations, China
Department of Oncology, University of Miami School of Medicine, Florida.