Hypertension, Vol 2, 686-694, Copyright © 1980 by American Heart Association
AW Voors, LS Webber and GS Berenson
Cardiovascular risk factors in childhood were assessed by re-examining a
random sample of 278 children stratified by diastolic blood pressure (BP),
obtained from 3524 children aged 7-15 years in an entire geographic
biracial community (Bogalusa). Re-examination included plasma renin and
serum electrolytes, 24-hour urine electrolytes, heart rates, and BP at rest
and in response to standardized physical stresses (orthostatic, isometric
handgrip, and cold pressor tests). The BP responses in these tests were not
increased in the high BP strata, which argues against a prevailing labile
phase in early essential hypertension. Black children tended toward larger
BP responses than whites. In black boys of the high BP stratum (n = 25),
systolic supine or stressed BP were higher than for other race-sex groups;
these pressures were associated negatively with plasma renin activity,
which was low. White children in the high BP strata had increased heart
rates, possibly indicating hyperkinetic circulation. These findings
indicate that multiple mechanisms operate to contol BP at different
intensities for black and white children.
ARTICLES
Racial contrasts in cardiovascular response tests for children from a total community
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