(Hypertension. 1996;27:799-803.)
© 1996 American Heart Association, Inc.
Articles |
Remodeling of the Radial Artery in Response to a Chronic Increase in Shear Stress
From the Departments of Internal Medicine (X.G., J.-J.M., M.S.) and Pharmacology (P.B., S.L.), Broussais Hospital, Paris; INSERM U337 (X.G., S.L., M.S.), Paris; and the Centre Hospitalier F.H. Manhes, Fleury-Mérogis (G.L.), France.
Abstract Chronic changes in large artery blood flow rates induce corresponding adjustments in arterial diameter, but little is known about structural adaptations of the vessel wall in humans. We used a high-resolution echo-tracking system to measure radial artery internal diameter, wall thickness, and mean blood flow on both arms of 11 patients with end-stage renal disease. Measurements were performed on the wrist side of the arteriovenous fistula. The contralateral radial artery was investigated as control. Wall cross-sectional area, circumferential wall stress, and mean wall shear stress were calculated. Results indicate a sixfold increase in blood flow on the side of the arteriovenous fistula compared with the control side, with a 1.4-fold increase in internal diameter. The diameter enlargement was sufficient to normalize wall shear stress. Changes in diameter were not associated with arterial wall hypertrophy because wall cross-sectional area was not increased and rather suggest a "remodeling" of the arterial wall. For the same level of blood pressure, circumferential wall stress was increased on the side of the arteriovenous fistula. These results suggest that the structural adaptations of the arterial wall to a chronic increase in blood flow normalize wall shear stress and overcome stretch-induced changes in the particular circumstance of arteriovenous fistula.
Key Words: arteries • kidney • hemodynamics • blood flow velocity • arteriovenous fistula
This article has been cited by other articles:
 |
|
 |
|
  M. R. Scheltinga, F. van Hoek, and C. M. A. Bruijninckx Time of onset in haemodialysis access-induced distal ischaemia (HAIDI) is related to the access type Nephrol. Dial. Transplant., October 1, 2009; 24(10): 3198 - 3204. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Garcia and G. S. Kassab Right coronary artery becomes stiffer with increase in elastin and collagen in right ventricular hypertrophy J Appl Physiol, April 1, 2009; 106(4): 1338 - 1346. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Kozakova, C. Palombo, M. Paterni, C.-H. Anderwald, T. Konrad, M.-P. Colgan, A. Flyvbjerg, J. Dekker, and on behalf of the Relationship between Insulin Sens Body Composition and Common Carotid Artery Remodeling in a Healthy Population J. Clin. Endocrinol. Metab., September 1, 2008; 93(9): 3325 - 3332. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Vita, M. Holbrook, J. Palmisano, S. M. Shenouda, W. B. Chung, N. M. Hamburg, B. R. Eskenazi, L. Joseph, and O. M. Shapira Flow-Induced Arterial Remodeling Relates to Endothelial Function in the Human Forearm Circulation, June 17, 2008; 117(24): 3126 - 3133. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Hope, A. K. Meadows, T. A. Hope, K. G. Ordovas, G. P. Reddy, M. T. Alley, and C. B. Higgins Evaluation of Bicuspid Aortic Valve and Aortic Coarctation With 4D Flow Magnetic Resonance Imaging Circulation, May 27, 2008; 117(21): 2818 - 2819. [Full Text] [PDF]
|
|
|
|
|
|
C. Basile, C. Lomonte, L. Vernaglione, F. Casucci, M. Antonelli, and N. Losurdo The relationship between the flow of arteriovenous fistula and cardiac output in haemodialysis patients Nephrol. Dial. Transplant., January 1, 2008; 23(1): 282 - 287. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Fukui, H. Fukuda, K. Toda, M. Yoshitatsu, T. Funatsu, T. Masai, and Y. Miyamoto Remodeling of the radial artery anastomosed to the internal thoracic artery as a composite straight graft. J. Thorac. Cardiovasc. Surg., November 1, 2007; 134(5): 1136 - 1142. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Tuka, M. Slavikova, J. Svobodova, and J. Malik Diabetes and distal access location are associated with higher wall shear rate in feeding artery of PTFE grafts Nephrol. Dial. Transplant., October 1, 2006; 21(10): 2821 - 2824. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. D. Bui, I. L. Gordon, A. Parashar, D. Vo, and S. E. Wilson Resistance Within Hemodialysis Shunts Predicts Patency Vascular and Endovascular Surgery, August 1, 2006; 40(4): 295 - 302. [Abstract] [PDF]
|
|
|
|
 |
|
 T. Nagaoka and A. Yoshida Noninvasive evaluation of wall shear stress on retinal microcirculation in humans. Invest. Ophthalmol. Vis. Sci., March 1, 2006; 47(3): 1113 - 1119. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Asif, P. Roy-Chaudhury, and G. A. Beathard Early Arteriovenous Fistula Failure: A Logical Proposal for When and How to Intervene Clin. J. Am. Soc. Nephrol., March 1, 2006; 1(2): 332 - 339. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. W.H. van der Heijden, Y. P.G. Essers, M. E.A. Spaanderman, J. G.R. De Mey, G. J.J.M. van Eys, and L. L.H. Peeters Uterine Artery Remodeling in Pseudopregnancy Is Comparable to That in Early Pregnancy Biol Reprod, December 1, 2005; 73(6): 1289 - 1293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. B. Barner Vascular remodeling as a biologic principle: Is the ulnar artery an exception? J. Thorac. Cardiovasc. Surg., July 1, 2005; 130(1): 7 - 8. [Full Text] [PDF]
|
|
|
|
|
|
T. Nagaoka, Y. Ishii, T. Takeuchi, A. Takahashi, E. Sato, and A. Yoshida Relationship between the Parameters of Retinal Circulation Measured by Laser Doppler Velocimetry and a Marker of Early Systemic Atherosclerosis Invest. Ophthalmol. Vis. Sci., February 1, 2005; 46(2): 720 - 725. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. G. Affleck, H. B. Barner, M. S. Bailey, L. A. Perry, H. Maniar, S. M. Prasad, and R. J. Damiano Jr Flow Dynamics of the Internal Thoracic and Radial Artery T-Graft Ann. Thorac. Surg., October 1, 2004; 78(4): 1290 - 1294. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Konner, B. Nonnast-Daniel, and E. Ritz The Arteriovenous Fistula J. Am. Soc. Nephrol., June 1, 2003; 14(6): 1669 - 1680. [Full Text] [PDF]
|
|
|
|
|
|
H. V. Riekkinen, K. O. Karkola, and A. Kankainen The radial artery is larger than the ulnar Ann. Thorac. Surg., March 1, 2003; 75(3): 882 - 884. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Tuttle, T. L. Hahn, B. M. Sanders, F. A. Witzmann, S. J. Miller, M. C. Dalsing, and J. L. Unthank Impaired collateral development in mature rats Am J Physiol Heart Circ Physiol, July 1, 2002; 283(1): H146 - H155. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-M. Corpataux, E. Haesler, P. Silacci, H. B. Ris, and D. Hayoz Low-pressure environment and remodelling of the forearm vein in Brescia-Cimino haemodialysis access Nephrol. Dial. Transplant., June 1, 2002; 17(6): 1057 - 1062. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. B. Barner Remodeling of arterial conduits in coronary grafting Ann. Thorac. Surg., April 1, 2002; 73(4): 1341 - 1345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Tuttle, R. D. Nachreiner, A. S. Bhuller, K. W. Condict, B. A. Connors, B. P. Herring, M. C. Dalsing, and J. L. Unthank Shear level influences resistance artery remodeling: wall dimensions, cell density, and eNOS expression Am J Physiol Heart Circ Physiol, September 1, 2001; 281(3): H1380 - H1389. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. A Dinenno, H. Tanaka, K. D Monahan, C. M Clevenger, I. Eskurza, C. A DeSouza, and D. R Seals Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men J. Physiol., July 1, 2001; 534(1): 287 - 295. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Lu, J. B. Zhao, G. R. Wang, H. Gregersen, and G. S. Kassab Remodeling of the zero-stress state of femoral arteries in response to flow overload Am J Physiol Heart Circ Physiol, April 1, 2001; 280(4): H1547 - H1559. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Gaudino, F. Glieca, C. Trani, A. Lupi, M. A. Mazzari, G. Schiavoni, and G. Possati Midterm endothelial function and remodeling of radial artery grafts anastomosed to the aorta J. Thorac. Cardiovasc. Surg., August 1, 2000; 120(2): 298 - 301. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Gnasso, C. Motti, C. Irace, C. Carallo, L. Liberatoscioli, S. Bernardini, R. Massoud, P. L. Mattioli, G. Federici, and C. Cortese Genetic Variation in Human Stromelysin Gene Promoter and Common Carotid Geometry in Healthy Male Subjects Arterioscler Thromb Vasc Biol, June 1, 2000; 20(6): 1600 - 1605. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Malek, S. L. Alper, and S. Izumo Hemodynamic Shear Stress and Its Role in Atherosclerosis JAMA, December 1, 1999; 282(21): 2035 - 2042. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Linderman and M. A. Boegehold Growth-related changes in the influence of nitric oxide on arteriolar tone Am J Physiol Heart Circ Physiol, October 1, 1999; 277(4): H1570 - H1578. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Marchais, F. Metivier, A. P. Guerin, and G. M. London Association of hyperphosphataemia with haemodynamic disturbances in end-stage renal disease Nephrol. Dial. Transplant., September 1, 1999; 14(9): 2178 - 2183. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Hayakawa, G. Takemura, J. Misao, M. Kanoh, M. Ohno, H. Ohashi, H. Takatsu, H. Ito, K. Fukuda, T. Fujiwara, et al. Apoptosis and Overexpression of Bax Protein and bax mRNA in Smooth Muscle Cells Within Intimal Hyperplasia of Human Radial Arteries : Analysis With Arteriovenous Fistulas Used for Hemodialysis Arterioscler Thromb Vasc Biol, September 1, 1999; 19(9): 2066 - 2077. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Carallo, C. Irace, A. Pujia, M. S. De Franceschi, A. Crescenzo, C. Motti, C. Cortese, P. L. Mattioli, and A. Gnasso Evaluation of Common Carotid Hemodynamic Forces : Relations With Wall Thickening Hypertension, August 1, 1999; 34(2): 217 - 221. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Blacher, B. Pannier, A. P. Guerin, S. J. Marchais, M. E. Safar, and G. M. London Carotid Arterial Stiffness as a Predictor of Cardiovascular and All-Cause Mortality in End-Stage Renal Disease Hypertension, September 1, 1998; 32(3): 570 - 574. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Safar, G. M. London, R. Asmar, and E. D. Frohlich Recent Advances on Large Arteries in Hypertension Hypertension, July 1, 1998; 32(1): 156 - 161. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Blacher, K. Demuth, A. P. Guerin, M. E. Safar, N. Moatti, and G. M. London Influence of Biochemical Alterations on Arterial Stiffness in Patients With End-stage Renal Disease Arterioscler Thromb Vasc Biol, April 1, 1998; 18(4): 535 - 541. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Unthank, S. W. Fath, H. M. Burkhart, S. C. Miller, and M. C. Dalsing Wall Remodeling During Luminal Expansion of Mesenteric Arterial Collaterals in the Rat Circ. Res., November 1, 1996; 79(5): 1015 - 1023. [Abstract] [Full Text]
|
|