This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Rakic, V. Articles by Beilin, L. J. Search for Related Content PubMed PubMed Citation Articles by Rakic, V. Articles by Beilin, L. J. Related Collections Secondary prevention Other hypertension Epidemiology

(Hypertension. 1999;33:869-873.)
© 1999 American Heart Association, Inc.

Scientific Contributions

Effects of Coffee on Ambulatory Blood Pressure in Older Men and Women

A Randomized Controlled Trial

Valentina Rakic; Valerie Burke; Lawrence J. Beilin

From the University Department of Medicine, Royal Perth Hospital and West Australian Heart Research Institute, Perth, Western Australia.

Abstract—This study assessed the effects of regular coffee drinking on 24-hour ambulatory blood pressure (ABP) in normotensive and hypertensive older men and women. Twenty-two normotensive and 26 hypertensive, nonsmoking men and women, with a mean age of 72.1 years (range, 54 to 89 years), took part in the study. After 2 weeks of a caffeine-free diet, subjects were randomized to continue with the caffeine-free diet and abstain from caffeine-containing drinks or drink instant coffee (5 cups per day, equivalent to 300 mg caffeine per day) in addition to the caffeine-free diet for a further 2 weeks. Change in systolic and diastolic blood pressures (SBP, DBP) determined by 24-hour ambulatory BP monitoring showed significant interactions between coffee drinking and hypertension status. In the hypertensive group, rise in mean 24-hour SBP was greater by 4.8 (SEM, 1.3) mm Hg (P=0.031) and increase in mean 24-hour DBP was higher by 3.0 (1.0) mm Hg (P=0.010) in coffee drinkers than in abstainers. There were no significant differences between abstainers and coffee drinkers in the normotensive group for 24-hour, daytime, or nighttime SBP or DBP. In older men and women with treated or untreated hypertension, ABP increased in coffee drinkers and decreased in abstainers. Restriction of coffee intake may be beneficial in older hypertensive individuals.

Key Words: coffee • blood pressure, ambulatory • aged • controlled trial

This article has been cited by other articles:

				C. Vlachopoulos, D. Panagiotakos, N. Ioakeimidis, I. Dima, and C. Stefanadis Chronic coffee consumption has a detrimental effect on aortic stiffness and wave reflections Am. J. Clinical Nutrition, June 1, 2005; 81(6): 1307 - 1312. [Abstract] [Full Text] [PDF]

				J. E. James Critical Review of Dietary Caffeine and Blood Pressure: A Relationship That Should Be Taken More Seriously Psychosom Med, January 1, 2004; 66(1): 63 - 71. [Abstract] [Full Text] [PDF]

				R. Corti, C. Binggeli, I. Sudano, L. Spieker, E. Hanseler, F. Ruschitzka, W. F. Chaplin, T. F. Luscher, and G. Noll Coffee Acutely Increases Sympathetic Nerve Activity and Blood Pressure Independently of Caffeine Content: Role of Habitual Versus Nonhabitual Drinking Circulation, December 3, 2002; 106(23): 2935 - 2940. [Abstract] [Full Text] [PDF]

				J. D. Lane, C. F. Pieper, B. G. Phillips-Bute, J. E. Bryant, and C. M. Kuhn Caffeine Affects Cardiovascular and Neuroendocrine Activation at Work and Home Psychosom Med, July 1, 2002; 64(4): 595 - 603. [Abstract] [Full Text] [PDF]

				M. G. Warner Complementary and Alternative Therapies for Hypertension Complementary Health Practice Review, October 1, 2000; 6(1): 11 - 19. [PDF]

				T. R. Hartley, B. H. Sung, G. A. Pincomb, T. L. Whitsett, M. F. Wilson, and W. R. Lovallo Hypertension Risk Status and Effect of Caffeine on Blood Pressure Hypertension, July 1, 2000; 36(1): 137 - 141. [Abstract] [Full Text] [PDF]