Hypertension. 2001;37:1045-1046
(Hypertension. 2001;37:1045.)
© 2001 American Heart Association, Inc.
David H.P. Streeten, MB, DPhil, FRCP
Harold Smulyan;
Arnold Mose
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Introduction
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David Streeten was born, educated, and began his lifes
work in South
Africa. He distinguished himself early by graduating
with distinction
from the University of South Africa in Bloemfontein
and with
first-class honors from the Medical School at the
University of
Witwatersrand. After 2 years as a house officer,
he moved to
the University of Oxford, where he obtained his
DPhil degree while
collaborating extensively with E.M. Vaughn
Williams. Although this
experience launched his research career,
the subject of his
investigations, intestinal motility, was
never revisited. From Oxford,
he came to the United States,
where he trained with George Thorn in
Endocrinology at the
Peter Bent Brigham Hospital. There, his research
centered about
the actions of corticotropin and hydrocortisone. His
first
full-time faculty position was in Ann Arbor at the University
of
Michigan as an Assistant Professor in the Division of Endocrinology
and
Metabolism. While working there with Drs Jerome Conn and
Stefan Fajans, he established a novel bioassay for the newly
discovered
aldosterone. This assay was used to make the first
confirmed diagnosis of primary aldosteronism as a new secondary
cause
of hypertension. While in Ann Arbor, he also became interested
in
periodic paralysis, diabetes, and autonomic control of the
circulation,
which occupied much of his research attention
for the rest of his
career. In 1960, we had the good fortune
to recruit him to the
University Hospital of the State University
of New York at Syracuse,
where he began and led the Endocrinology
Division in the Department of
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