Hypertension. 2001;38:938-942
doi: 10.1161/hy1001.096358
doi: 10.1161/hy1001.096358
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(Hypertension. 2001;38:938.)
© 2001 American Heart Association, Inc.
Fourth Workshop on Structure and Function of Large Arteries |
Arterial Calcifications, Arterial Stiffness, and Cardiovascular Risk in End-Stage Renal Disease
From Service de Médecine Interne, Hôpital Broussais, AP-HP (J.B.), Paris, France; and Service d’Hémodialyse, Hôpital F.H. Manhès (A.P.G., B.P., S.J.M., G.M.L.), Fleury-Mérogis, France.
Correspondence to Dr Jacques Blacher, Service de Médecine Interne, Hôpital Broussais, AP-HP, 96 Rue Didot, 75014 Paris, France. E-mail jacques.blacher{at}brs.ap-hop-paris.fr
Abstract
Abstract—— To test the predictive values of and independent contributions to cardiovascular and all-cause mortality of various arterial parameters exploring characteristics of the arterial wall at different sites, we studied prospectively 110 stable end-stage renal disease patients on hemodialysis. These parameters involved carotid diameter, carotid intima-media thickness, carotid compliance, carotid distensibility, carotid incremental elastic modulus, aortic diameter, aortic pulse wave velocity, and the presence of arterial calcifications measured at the sites of the carotid artery, abdominal aorta, iliofemoral axis, and legs. The presence of calcifications was analyzed semiquantitatively as a score (0 to 4) according to the number of arterial sites with calcifications. During a follow-up of 53±21 months (mean±SD), 25 cardiovascular and 14 noncardiovascular deaths occurred. In univariate analysis, the carotid incremental elastic modulus was the most closely related to prognosis. Risk of death increased with the number of vascular sites involved by calcifications. Moreover, information (in terms of prediction) given by carotid elastic incremental modulus was additive to the presence and extent of vascular calcification-related prediction value. Adjusted hazard ratios of all-cause and cardiovascular mortality for an increase of 1 unit in calcification score were 1.9 (95% confidence interval [CI], 1.4 to 2.6) and 2.6 (95% CI, 1.5 to 4.4), respectively (P<0.001 for both). Adjusted hazard ratios of all-cause and cardiovascular mortality for a 1-SD increase in carotid incremental elastic modulus were 1.6 (95% CI, 1.2 to 2.2) and 1.7 (95% CI, 1.2 to 2.4), respectively (P<0.01 for both). The results of this study showed that the presence and extent of vascular calcifications were strong predictors of cardiovascular and all-cause mortality. Carotid incremental elastic modulus gave additional predictive value.
Key Words: renal disease • cardiovascular diseases • arteries • mortality • calcifications
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|
|
|
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|
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|
|
|
|
|
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|
|
|
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|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
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M. C. Matteucci, E. Wuhl, S. Picca, A. Mastrostefano, G. Rinelli, C. Romano, G. Rizzoni, O. Mehls, G. de Simone, F. Schaefer, et al. Left Ventricular Geometry in Children with Mild to Moderate Chronic Renal Insufficiency J. Am. Soc. Nephrol., January 1, 2006; 17(1): 218 - 226. [Abstract] [Full Text] [PDF]
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 J. J. Schucker and K. E. Ward Hyperphosphatemia and phosphate binders Am. J. Health Syst. Pharm., November 15, 2005; 62(22): 2355 - 2361. [Abstract] [Full Text] [PDF]
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E. Zitt and A. R. Rosenkranz Vascular calcification and increased mortality in dialysis patients: is the baroreflex sensitivity the answer? Nephrol. Dial. Transplant., November 1, 2005; 20(11): 2580 - 2580. [Full Text] [PDF]
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A K Nightingale and J D Horowitz Aortic sclerosis: not an innocent murmur but a marker of increased cardiovascular risk Heart, November 1, 2005; 91(11): 1389 - 1393. [Abstract] [Full Text] [PDF]
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M. W. Merx, C. Schafer, R. Westenfeld, V. Brandenburg, S. Hidajat, C. Weber, M. Ketteler, and W. Jahnen-Dechent Myocardial Stiffness, Cardiac Remodeling, and Diastolic Dysfunction in Calcification-Prone Fetuin-A-Deficient Mice J. Am. Soc. Nephrol., November 1, 2005; 16(11): 3357 - 3364. [Abstract] [Full Text] [PDF]
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C. R. Nolan Strategies for Improving Long-Term Survival in Patients with ESRD J. Am. Soc. Nephrol., November 1, 2005; 16(11_suppl_2): S120 - S127. [Abstract] [Full Text] [PDF]
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J. L. Reynolds, J. N. Skepper, R. McNair, T. Kasama, K. Gupta, P. L. Weissberg, W. Jahnen-Dechent, and C. M. Shanahan Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification J. Am. Soc. Nephrol., October 1, 2005; 16(10): 2920 - 2930. [Abstract] [Full Text] [PDF]
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K. A. Hruska, S. Mathew, and G. Saab Bone Morphogenetic Proteins in Vascular Calcification Circ. Res., July 22, 2005; 97(2): 105 - 114. [Abstract] [Full Text] [PDF]
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M. F. O'Rourke and M. E. Safar Relationship Between Aortic Stiffening and Microvascular Disease in Brain and Kidney: Cause and Logic of Therapy Hypertension, July 1, 2005; 46(1): 200 - 204. [Abstract] [Full Text] [PDF]
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L. J. Chesterton, M. K. Sigrist, T. Bennett, M. W. Taal, and C. W. McIntyre Reduced baroreflex sensitivity is associated with increased vascular calcification and arterial stiffness Nephrol. Dial. Transplant., June 1, 2005; 20(6): 1140 - 1147. [Abstract] [Full Text] [PDF]
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C. A. Peralta, L. S. Hicks, G. M. Chertow, J. Z. Ayanian, E. Vittinghoff, F. Lin, and M. G. Shlipak Control of Hypertension in Adults With Chronic Kidney Disease in the United States Hypertension, June 1, 2005; 45(6): 1119 - 1124. [Abstract] [Full Text] [PDF]
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M. Litwin, E. Wuhl, C. Jourdan, J. Trelewicz, A. Niemirska, K. Fahr, K. Jobs, R. Grenda, Z. T. Wawer, P. Rajszys, et al. Altered Morphologic Properties of Large Arteries in Children with Chronic Renal Failure and after Renal Transplantation J. Am. Soc. Nephrol., May 1, 2005; 16(5): 1494 - 1500. [Abstract] [Full Text] [PDF]
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T. Takenaka and H. Suzuki New strategy to attenuate pulse wave velocity in haemodialysis patients Nephrol. Dial. Transplant., April 1, 2005; 20(4): 811 - 816. [Abstract] [Full Text] [PDF]
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G. M. Chertow and S. M. Moe Calcification or Classification? J. Am. Soc. Nephrol., February 1, 2005; 16(2): 293 - 295. [Full Text] [PDF]
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 O Kansu, M Ozbek, N Avcu, G Genctoy, H Kansu, and C Turgan The prevalence of carotid artery calcification on the panoramic radiographs of patients with renal disease Dentomaxillofac. Radiol., January 1, 2005; 34(1): 16 - 19. [Abstract] [Full Text] [PDF]
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Z. A. Massy, O. Ivanovski, T. Nguyen-Khoa, J. Angulo, D. Szumilak, N. Mothu, O. Phan, M. Daudon, B. Lacour, T. B. Drueke, et al. Uremia Accelerates both Atherosclerosis and Arterial Calcification in Apolipoprotein E Knockout Mice J. Am. Soc. Nephrol., January 1, 2005; 16(1): 109 - 116. [Abstract] [Full Text] [PDF]
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