Hypertension. 2001;38:938-942
doi: 10.1161/hy1001.096358
doi: 10.1161/hy1001.096358
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Hypertension. 2001;38:938.)
© 2001 American Heart Association, Inc.
Fourth Workshop on Structure and Function of Large Arteries |
Arterial Calcifications, Arterial Stiffness, and Cardiovascular Risk in End-Stage Renal Disease
From Service de Médecine Interne, Hôpital Broussais, AP-HP (J.B.), Paris, France; and Service d’Hémodialyse, Hôpital F.H. Manhès (A.P.G., B.P., S.J.M., G.M.L.), Fleury-Mérogis, France.
Correspondence to Dr Jacques Blacher, Service de Médecine Interne, Hôpital Broussais, AP-HP, 96 Rue Didot, 75014 Paris, France. E-mail jacques.blacher{at}brs.ap-hop-paris.fr
Abstract
Abstract—— To test the predictive values of and independent contributions to cardiovascular and all-cause mortality of various arterial parameters exploring characteristics of the arterial wall at different sites, we studied prospectively 110 stable end-stage renal disease patients on hemodialysis. These parameters involved carotid diameter, carotid intima-media thickness, carotid compliance, carotid distensibility, carotid incremental elastic modulus, aortic diameter, aortic pulse wave velocity, and the presence of arterial calcifications measured at the sites of the carotid artery, abdominal aorta, iliofemoral axis, and legs. The presence of calcifications was analyzed semiquantitatively as a score (0 to 4) according to the number of arterial sites with calcifications. During a follow-up of 53±21 months (mean±SD), 25 cardiovascular and 14 noncardiovascular deaths occurred. In univariate analysis, the carotid incremental elastic modulus was the most closely related to prognosis. Risk of death increased with the number of vascular sites involved by calcifications. Moreover, information (in terms of prediction) given by carotid elastic incremental modulus was additive to the presence and extent of vascular calcification-related prediction value. Adjusted hazard ratios of all-cause and cardiovascular mortality for an increase of 1 unit in calcification score were 1.9 (95% confidence interval [CI], 1.4 to 2.6) and 2.6 (95% CI, 1.5 to 4.4), respectively (P<0.001 for both). Adjusted hazard ratios of all-cause and cardiovascular mortality for a 1-SD increase in carotid incremental elastic modulus were 1.6 (95% CI, 1.2 to 2.2) and 1.7 (95% CI, 1.2 to 2.4), respectively (P<0.01 for both). The results of this study showed that the presence and extent of vascular calcifications were strong predictors of cardiovascular and all-cause mortality. Carotid incremental elastic modulus gave additional predictive value.
Key Words: renal disease • cardiovascular diseases • arteries • mortality • calcifications
This article has been cited by other articles:
 |
|
 |
|
  Q. Guo, J. J. Carrero, X. Yu, P. Barany, A. R. Qureshi, M. Eriksson, B. Anderstam, M. Chmielewski, O. Heimburger, P. Stenvinkel, et al. Associations of VEGF and its receptors sVEGFR-1 and -2 with cardiovascular disease and survival in prevalent haemodialysis patients Nephrol. Dial. Transplant., November 1, 2009; 24(11): 3468 - 3473. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Sengstock, R. L. Sands, B. W. Gillespie, X. Zhang, M. Kiser, G. Eisele, P. Vaitkevicius, M. Kuhlmann, N. W. Levin, A. Hinderliter, et al. Dominance of traditional cardiovascular risk factors over renal function in predicting arterial stiffness in subjects with chronic kidney disease Nephrol. Dial. Transplant., October 23, 2009; (2009) gfp559v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Jamal, D. Fitchett, C. E. Lok, D. C. Mendelssohn, and R. T. Tsuyuki The effects of calcium-based versus non-calcium-based phosphate binders on mortality among patients with chronic kidney disease: a meta-analysis Nephrol. Dial. Transplant., October 1, 2009; 24(10): 3168 - 3174. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. C. Barreto, D. V. Barreto, S. Liabeuf, N. Meert, G. Glorieux, M. Temmar, G. Choukroun, R. Vanholder, Z. A. Massy, and on behalf of the European Uremic Toxin Work Group Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients Clin. J. Am. Soc. Nephrol., October 1, 2009; 4(10): 1551 - 1558. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Navarro-Gonzalez, C. Mora-Fernandez, M. Muros, H. Herrera, and J. Garcia Mineral Metabolism and Inflammation in Chronic Kidney Disease Patients: A Cross-Sectional Study Clin. J. Am. Soc. Nephrol., October 1, 2009; 4(10): 1646 - 1654. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Moore, J. Yee, H. Malluche, D. S. Rao, M.-C. Monier-Faugere, E. Adams, O. Daramola-Ogunwuyi, H. Fehmi, S. Bhat, and Y. Osman-Malik Relationship between Bone Histology and Markers of Bone and Mineral Metabolism in African-American Hemodialysis Patients Clin. J. Am. Soc. Nephrol., September 1, 2009; 4(9): 1484 - 1493. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. LeBeouf, F. Mac-Way, M. S. Utescu, N. Chbinou, P. Douville, S. Desmeules, and M. Agharazii Effects of acute variation of dialysate calcium concentrations on arterial stiffness and aortic pressure waveform Nephrol. Dial. Transplant., August 4, 2009; (2009) gfp351v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Koleganova, G. Piecha, E. Ritz, P. Schirmacher, A. Muller, H.-P. Meyer, and M.-L. Gross Arterial calcification in patients with chronic kidney disease Nephrol. Dial. Transplant., August 1, 2009; 24(8): 2488 - 2496. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. C. O'Neill, M. K. Sigrist, and C. W. McIntyre Plasma pyrophosphate and vascular calcification in chronic kidney disease Nephrol. Dial. Transplant., July 24, 2009; (2009) gfp362v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Mizobuchi, D. Towler, and E. Slatopolsky Vascular Calcification: The Killer of Patients with Chronic Kidney Disease J. Am. Soc. Nephrol., July 1, 2009; 20(7): 1453 - 1464. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. G. Hage, R. Venkataraman, G. J. Zoghbi, G. J. Perry, A. M. DeMattos, and A. E. Iskandrian The scope of coronary heart disease in patients with chronic kidney disease. J. Am. Coll. Cardiol., June 9, 2009; 53(23): 2129 - 2140. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. V. Barreto, F. C. Barreto, S. Liabeuf, M. Temmar, F. Boitte, G. Choukroun, A. Fournier, and Z. A. Massy Vitamin D Affects Survival Independently of Vascular Calcification in Chronic Kidney Disease Clin. J. Am. Soc. Nephrol., June 1, 2009; 4(6): 1128 - 1135. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Westenfeld, C. Schafer, T. Kruger, C. Haarmann, L. J. Schurgers, C. Reutelingsperger, O. Ivanovski, T. Drueke, Z. A. Massy, M. Ketteler, et al. Fetuin-A Protects against Atherosclerotic Calcification in CKD J. Am. Soc. Nephrol., June 1, 2009; 20(6): 1264 - 1274. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Panizo, A. Cardus, M. Encinas, E. Parisi, P. Valcheva, S. Lopez-Ongil, B. Coll, E. Fernandez, and J. M. Valdivielso RANKL Increases Vascular Smooth Muscle Cell Calcification Through a RANK-BMP4-Dependent Pathway Circ. Res., May 8, 2009; 104(9): 1041 - 1048. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Madero, C. L. Wassel, C. A. Peralta, S. S. Najjar, K. Sutton-Tyrrell, L. Fried, R. Canada, A. Newman, M. G. Shlipak, M. J. Sarnak, et al. Cystatin C Associates with Arterial Stiffness in Older Adults J. Am. Soc. Nephrol., May 1, 2009; 20(5): 1086 - 1093. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. S. DeLoach, M. M. Joffe, X. Mai, S. Goral, and S. E. Rosas Aortic calcification predicts cardiovascular events and all-cause mortality in renal transplantation Nephrol. Dial. Transplant., April 1, 2009; 24(4): 1314 - 1319. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Adragao, A. Pires, R. Birne, J. D. Curto, C. Lucas, M. Goncalves, and A. P. Negrao A plain X-ray vascular calcification score is associated with arterial stiffness and mortality in dialysis patients Nephrol. Dial. Transplant., March 1, 2009; 24(3): 997 - 1002. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Jaroszynski, E. Czekajska-Chechab, A. Drelich-Zbroja, T. Zapolski, and A. Ksiazek Spatial QRS-T angle in peritoneal dialysis patients: association with carotid artery atherosclerosis, coronary artery calcification and troponin T Nephrol. Dial. Transplant., March 1, 2009; 24(3): 1003 - 1008. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Belozeroff, W. G. Goodman, L. Ren, and K. Kalantar-Zadeh Cinacalcet Lowers Serum Alkaline Phosphatase in Maintenance Hemodialysis Patients Clin. J. Am. Soc. Nephrol., March 1, 2009; 4(3): 673 - 679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. J. Matias, C. Ferreira, C. Jorge, M. Borges, I. Aires, T. Amaral, C. Gil, J. Cortez, and A. Ferreira 25-Hydroxyvitamin D3, arterial calcifications and cardiovascular risk markers in haemodialysis patients Nephrol. Dial. Transplant., February 1, 2009; 24(2): 611 - 618. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Russo, L. F. Morrone, S. Brancaccio, P. Napolitano, E. Salvatore, R. Spadola, M. Imbriaco, C. V. Russo, and V. E. Andreucci Pulse Pressure and Presence of Coronary Artery Calcification Clin. J. Am. Soc. Nephrol., February 1, 2009; 4(2): 316 - 322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Adragao, J. Herberth, M.-C. Monier-Faugere, A. J. Branscum, A. Ferreira, J. M. Frazao, J. Dias Curto, and H. H. Malluche Low Bone Volume--A Risk Factor for Coronary Calcifications in Hemodialysis Patients Clin. J. Am. Soc. Nephrol., February 1, 2009; 4(2): 450 - 455. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Isakova, O. M. Gutierrez, Y. Chang, A. Shah, H. Tamez, K. Smith, R. Thadhani, and M. Wolf Phosphorus Binders and Survival on Hemodialysis J. Am. Soc. Nephrol., February 1, 2009; 20(2): 388 - 396. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Y.-M. Wang VASCULAR AND OTHER TISSUE CALCIFICATION IN PERITONEAL DIALYSIS PATIENTS Perit. Dial. Int., February 1, 2009; 29(Supplement_2): S9 - S14. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Rodriguez-Garcia, C. Gomez-Alonso, M. Naves-Diaz, J. B. Diaz-Lopez, C. Diaz-Corte, J. B. Cannata-Andia, and the Asturias Study Group Vascular calcifications, vertebral fractures and mortality in haemodialysis patients Nephrol. Dial. Transplant., January 1, 2009; 24(1): 239 - 246. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Evenepoel, R. Selgas, F. Caputo, L. Foggensteiner, J. G. Heaf, A. Ortiz, A. Kelly, S. Chasan-Taber, A. Duggal, and S. Fan Efficacy and safety of sevelamer hydrochloride and calcium acetate in patients on peritoneal dialysis Nephrol. Dial. Transplant., January 1, 2009; 24(1): 278 - 285. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Toussaint, K. K. Lau, B. J. Strauss, K. R. Polkinghorne, and P. G. Kerr Determination and Validation of Aortic Calcification Measurement from Lateral Bone Densitometry in Dialysis Patients Clin. J. Am. Soc. Nephrol., January 1, 2009; 4(1): 119 - 127. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Toussaint, G. J. Elder, and P. G. Kerr Bisphosphonates in Chronic Kidney Disease; Balancing Potential Benefits and Adverse Effects on Bone and Soft Tissue Clin. J. Am. Soc. Nephrol., January 1, 2009; 4(1): 221 - 233. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. E Davies, K. H Parker, D. P Francis, A. D Hughes, and J. Mayet What is the role of the aorta in directing coronary blood flow? Heart, December 1, 2008; 94(12): 1545 - 1547. [Full Text] [PDF]
|
|
|
|
|
|
K. Amann Media Calcification and Intima Calcification Are Distinct Entities in Chronic Kidney Disease Clin. J. Am. Soc. Nephrol., November 1, 2008; 3(6): 1599 - 1605. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. G. Arroyo, M. A. Hayes, J. DeLay, C. Rao, B. Duncan, and L. Viel Arterial Calcification in Race Horses Vet. Pathol., September 1, 2008; 45(5): 617 - 625. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. London, S. J. Marchais, A. P. Guerin, P. Boutouyrie, F. Metivier, and M.-C. de Vernejoul Association of Bone Activity, Calcium Load, Aortic Stiffness, and Calcifications in ESRD J. Am. Soc. Nephrol., September 1, 2008; 19(9): 1827 - 1835. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Dorr, K. Empen, D. M Robinson, H. Wallaschofski, S. B Felix, and H. Volzke The association of thyroid function with carotid artery plaque burden and strokes in a population-based sample from a previously iodine-deficient area Eur. J. Endocrinol., August 1, 2008; 159(2): 145 - 152. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Fernhall and S. Agiovlasitis Arterial function in youth: window into cardiovascular risk J Appl Physiol, July 1, 2008; 105(1): 325 - 333. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. P. How, D. L. Mason, and A. H. Lau Current Approaches in the Treatment of Chronic Kidney Disease Mineral and Bone Disorder Journal of Pharmacy Practice, June 1, 2008; 21(3): 196 - 213. [Abstract] [PDF]
|
|
|
|
|
|
P. Stenvinkel, J. J. Carrero, J. Axelsson, B. Lindholm, O. Heimburger, and Z. Massy Emerging Biomarkers for Evaluating Cardiovascular Risk in the Chronic Kidney Disease Patient: How Do New Pieces Fit into the Uremic Puzzle? Clin. J. Am. Soc. Nephrol., March 1, 2008; 3(2): 505 - 521. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Toussaint, K. K. Lau, B. J. Strauss, K. R. Polkinghorne, and P. G. Kerr Associations between vascular calcification, arterial stiffness and bone mineral density in chronic kidney disease Nephrol. Dial. Transplant., February 1, 2008; 23(2): 586 - 593. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Ferreira, J. M. Frazao, M.-C. Monier-Faugere, C. Gil, J. Galvao, C. Oliveira, J. Baldaia, I. Rodrigues, C. Santos, S. Ribeiro, et al. Effects of Sevelamer Hydrochloride and Calcium Carbonate on Renal Osteodystrophy in Hemodialysis Patients J. Am. Soc. Nephrol., February 1, 2008; 19(2): 405 - 412. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. S. DeLoach and R. R. Townsend Vascular Stiffness: Its Measurement and Significance for Epidemiologic and Outcome Studies Clin. J. Am. Soc. Nephrol., January 1, 2008; 3(1): 184 - 192. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Caglar, M. I. Yilmaz, M. Saglam, E. Cakir, C. Acikel, T. Eyileten, M. Yenicesu, Y. Oguz, A. Vural, J. J. Carrero, et al. Short-Term Treatment with Sevelamer Increases Serum Fetuin-A Concentration and Improves Endothelial Dysfunction in Chronic Kidney Disease Stage 4 Patients Clin. J. Am. Soc. Nephrol., January 1, 2008; 3(1): 61 - 68. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. L. Andress Bone and Mineral Guidelines for Patients with Chronic Kidney Disease: A Call for Revision Clin. J. Am. Soc. Nephrol., January 1, 2008; 3(1): 179 - 183. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Cunningham, J. Floege, G. London, M. Rodriguez, and C. M. Shanahan Clinical Outcomes in Secondary Hyperparathyroidism and the Potential Role of Calcimimetics NDT Plus, January 1, 2008; 1(suppl_1): i29 - i35. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kanno, T. Into, C. J. Lowenstein, and K. Matsushita Nitric oxide regulates vascular calcification by interfering with TGF-{beta} signalling Cardiovasc Res, January 1, 2008; 77(1): 221 - 230. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. K. Sigrist, M. W. Taal, P. Bungay, and C. W. McIntyre Progressive Vascular Calcification over 2 Years Is Associated with Arterial Stiffening and Increased Mortality in Patients with Stages 4 and 5 Chronic Kidney Disease Clin. J. Am. Soc. Nephrol., November 1, 2007; 2(6): 1241 - 1248. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. L. Schiffrin, M. L. Lipman, and J. F.E. Mann Chronic Kidney Disease: Effects on the Cardiovascular System Circulation, July 3, 2007; 116(1): 85 - 97. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yamada, S. Fujimoto, R. Nishiura, H. Komatsu, M. Tatsumoto, Y. Sato, S. Hara, S. Hisanaga, H. Ochiai, H. Nakao, et al. Risk factors of the progression of abdominal aortic calcification in patients on chronic haemodialysis Nephrol. Dial. Transplant., July 1, 2007; 22(7): 2032 - 2037. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Westenfeld, C. Schafer, R. Smeets, V. M. Brandenburg, J. Floege, M. Ketteler, and W. Jahnen-Dechent Fetuin-A (AHSG) prevents extraosseous calcification induced by uraemia and phosphate challenge in mice Nephrol. Dial. Transplant., June 1, 2007; 22(6): 1537 - 1546. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Garcia-Lopez, J. J. Carrero, M. E. Suliman, B. Lindholm, and P. Stenvinkel RISK FACTORS FOR CARDIOVASCULAR DISEASE IN PATIENTS UNDERGOING PERITONEAL DIALYSIS Perit. Dial. Int., June 1, 2007; 27(Supplement_2): S205 - S209. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Y.-M. Wang CARDIOVASCULAR RISK FACTORS IN PERITONEAL DIALYSIS PATIENTS REVISITED Perit. Dial. Int., June 1, 2007; 27(Supplement_2): S223 - S227. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Raggi, A. Bellasi, E. Ferramosca, G. A. Block, and P. Muntner Pulse Wave Velocity Is Inversely Related to Vertebral Bone Density in Hemodialysis Patients Hypertension, June 1, 2007; 49(6): 1278 - 1284. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Villa-Bellosta, Y. E. Bogaert, M. Levi, and V. Sorribas Characterization of Phosphate Transport in Rat Vascular Smooth Muscle Cells: Implications for Vascular Calcification Arterioscler Thromb Vasc Biol, May 1, 2007; 27(5): 1030 - 1036. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Muntner, E. Ferramosca, A. Bellasi, G. A. Block, and P. Raggi Development of a cardiovascular calcification index using simple imaging tools in haemodialysis patients Nephrol. Dial. Transplant., February 1, 2007; 22(2): 508 - 514. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Toussaint, K. K. Lau, K. R. Polkinghorne, and P. G. Kerr Measurement of vascular calcification using CT fistulograms Nephrol. Dial. Transplant., February 1, 2007; 22(2): 484 - 490. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. London, A. P. Guerin, F. H. Verbeke, B. Pannier, P. Boutouyrie, S. J. Marchais, and F. Metivier Mineral Metabolism and Arterial Functions in End-Stage Renal Disease: Potential Role of 25-Hydroxyvitamin D Deficiency J. Am. Soc. Nephrol., February 1, 2007; 18(2): 613 - 620. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Nikolov, N. Joki, T. Drueke, and Z. Massy Beyond phosphate--role of uraemic toxins in cardiovascular calcification Nephrol. Dial. Transplant., December 1, 2006; 21(12): 3354 - 3357. [Full Text] [PDF]
|
|
|
|
|
|
J. B. Cannata-Andia, M. Rodriguez-Garcia, N. Carrillo-Lopez, M. Naves-Diaz, and B. Diaz-Lopez Vascular Calcifications: Pathogenesis, Management, and Impact on Clinical Outcomes J. Am. Soc. Nephrol., December 1, 2006; 17(12_suppl_3): S267 - S273. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Galassi, D. M. Spiegel, A. Bellasi, G. A. Block, and P. Raggi Accelerated vascular calcification and relative hypoparathyroidism in incident haemodialysis diabetic patients receiving calcium binders Nephrol. Dial. Transplant., November 1, 2006; 21(11): 3215 - 3222. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C Vlachopoulos, K Aznaouridis, and C Stefanadis Clinical appraisal of arterial stiffness: the Argonauts in front of the Golden Fleece Heart, November 1, 2006; 92(11): 1544 - 1550. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Schillaci, M. Pirro, M. R. Mannarino, G. Pucci, G. Savarese, S. S. Franklin, and E. Mannarino Relation Between Renal Function Within the Normal Range and Central and Peripheral Arterial Stiffness in Hypertension Hypertension, October 1, 2006; 48(4): 616 - 621. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Tomiyama, A. Higa, M. A. Dalboni, M. Cendoroglo, S. A. Draibe, L. Cuppari, A. B. Carvalho, E. M. Neto, and M. E. F. Canziani The impact of traditional and non-traditional risk factors on coronary calcification in pre-dialysis patients Nephrol. Dial. Transplant., September 1, 2006; 21(9): 2464 - 2471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Ix, G. M. Chertow, M. G. Shlipak, V. M. Brandenburg, M. Ketteler, and M. A. Whooley Fetuin-A and kidney function in persons with coronary artery disease--data from the heart and soul study Nephrol. Dial. Transplant., August 1, 2006; 21(8): 2144 - 2151. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Briese, S. Wiesner, J. C. Will, A. Lembcke, B. Opgen-Rhein, R. Nissel, K.-D. Wernecke, J. Andreae, D. Haffner, and U. Querfeld Arterial and cardiac disease in young adults with childhood-onset end-stage renal disease--impact of calcium and vitamin D therapy Nephrol. Dial. Transplant., July 1, 2006; 21(7): 1906 - 1914. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. R. Wu-Wong, W. Noonan, J. Ma, D. Dixon, M. Nakane, A. L. Bolin, K. A. Koch, S. Postl, S. J. Morgan, and G. A. Reinhart Role of Phosphorus and Vitamin D Analogs in the Pathogenesis of Vascular Calcification J. Pharmacol. Exp. Ther., July 1, 2006; 318(1): 90 - 98. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ketteler, G. Schlieper, and J. Floege Calcification and Cardiovascular Health: New Insights Into an Old Phenomenon Hypertension, June 1, 2006; 47(6): 1027 - 1034. [Full Text] [PDF]
|
|
|
|
 |
|
 M. Boufi, P. Ghaffari, E. Allaire, H. Fessi, P. Ronco, and M. Vayssairat Foot Gangrene in Patients with End-Stage Renal Disease: A Case Control Study Angiology, May 1, 2006; 57(3): 355 - 361. [Abstract] [PDF]
|
|
|
|
|
|
H. M.H. Spronk Vitamin K Epoxide Reductase Complex and Vascular Calcification: Is This the Important Link Between Vitamin K and the Arterial Vessel Wall? Circulation, March 28, 2006; 113(12): 1550 - 1552. [Full Text] [PDF]
|
|
|
|
|
|
C. W. McIntyre Is it practical to screen dialysis patients for vascular calcification? Nephrol. Dial. Transplant., February 1, 2006; 21(2): 251 - 254. [Full Text] [PDF]
|
|
|
|
|
|
G. Jean, C. Chazot, and B. Charra Hyperphosphataemia and related mortality Nephrol. Dial. Transplant., February 1, 2006; 21(2): 273 - 280. [Full Text] [PDF]
|
|
|
|
|
|
H. Reichel Current treatment options in secondary renal hyperparathyroidism Nephrol. Dial. Transplant., January 1, 2006; 21(1): 23 - 28. [Full Text] [PDF]
|
|
|
|
|
|
M. C. Matteucci, E. Wuhl, S. Picca, A. Mastrostefano, G. Rinelli, C. Romano, G. Rizzoni, O. Mehls, G. de Simone, F. Schaefer, et al. Left Ventricular Geometry in Children with Mild to Moderate Chronic Renal Insufficiency J. Am. Soc. Nephrol., January 1, 2006; 17(1): 218 - 226. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. J. Schucker and K. E. Ward Hyperphosphatemia and phosphate binders Am. J. Health Syst. Pharm., November 15, 2005; 62(22): 2355 - 2361. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Zitt and A. R. Rosenkranz Vascular calcification and increased mortality in dialysis patients: is the baroreflex sensitivity the answer? Nephrol. Dial. Transplant., November 1, 2005; 20(11): 2580 - 2580. [Full Text] [PDF]
|
|
|
|
|
|
A K Nightingale and J D Horowitz Aortic sclerosis: not an innocent murmur but a marker of increased cardiovascular risk Heart, November 1, 2005; 91(11): 1389 - 1393. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. W. Merx, C. Schafer, R. Westenfeld, V. Brandenburg, S. Hidajat, C. Weber, M. Ketteler, and W. Jahnen-Dechent Myocardial Stiffness, Cardiac Remodeling, and Diastolic Dysfunction in Calcification-Prone Fetuin-A-Deficient Mice J. Am. Soc. Nephrol., November 1, 2005; 16(11): 3357 - 3364. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. R. Nolan Strategies for Improving Long-Term Survival in Patients with ESRD J. Am. Soc. Nephrol., November 1, 2005; 16(11_suppl_2): S120 - S127. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Reynolds, J. N. Skepper, R. McNair, T. Kasama, K. Gupta, P. L. Weissberg, W. Jahnen-Dechent, and C. M. Shanahan Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification J. Am. Soc. Nephrol., October 1, 2005; 16(10): 2920 - 2930. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Hruska, S. Mathew, and G. Saab Bone Morphogenetic Proteins in Vascular Calcification Circ. Res., July 22, 2005; 97(2): 105 - 114. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. F. O'Rourke and M. E. Safar Relationship Between Aortic Stiffening and Microvascular Disease in Brain and Kidney: Cause and Logic of Therapy Hypertension, July 1, 2005; 46(1): 200 - 204. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. J. Chesterton, M. K. Sigrist, T. Bennett, M. W. Taal, and C. W. McIntyre Reduced baroreflex sensitivity is associated with increased vascular calcification and arterial stiffness Nephrol. Dial. Transplant., June 1, 2005; 20(6): 1140 - 1147. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Peralta, L. S. Hicks, G. M. Chertow, J. Z. Ayanian, E. Vittinghoff, F. Lin, and M. G. Shlipak Control of Hypertension in Adults With Chronic Kidney Disease in the United States Hypertension, June 1, 2005; 45(6): 1119 - 1124. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Litwin, E. Wuhl, C. Jourdan, J. Trelewicz, A. Niemirska, K. Fahr, K. Jobs, R. Grenda, Z. T. Wawer, P. Rajszys, et al. Altered Morphologic Properties of Large Arteries in Children with Chronic Renal Failure and after Renal Transplantation J. Am. Soc. Nephrol., May 1, 2005; 16(5): 1494 - 1500. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Takenaka and H. Suzuki New strategy to attenuate pulse wave velocity in haemodialysis patients Nephrol. Dial. Transplant., April 1, 2005; 20(4): 811 - 816. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. Chertow and S. M. Moe Calcification or Classification? J. Am. Soc. Nephrol., February 1, 2005; 16(2): 293 - 295. [Full Text] [PDF]
|
|
|
|
 |
|
 O Kansu, M Ozbek, N Avcu, G Genctoy, H Kansu, and C Turgan The prevalence of carotid artery calcification on the panoramic radiographs of patients with renal disease Dentomaxillofac. Radiol., January 1, 2005; 34(1): 16 - 19. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. A. Massy, O. Ivanovski, T. Nguyen-Khoa, J. Angulo, D. Szumilak, N. Mothu, O. Phan, M. Daudon, B. Lacour, T. B. Drueke, et al. Uremia Accelerates both Atherosclerosis and Arterial Calcification in Apolipoprotein E Knockout Mice J. Am. Soc. Nephrol., January 1, 2005; 16(1): 109 - 116. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. H. Jung, K. R. Ma, and H. Han Elevated concentrations of cardiac troponins are associated with severe coronary artery calcification in asymptomatic haemodialysis patients Nephrol. Dial. Transplant., December 1, 2004; 19(12): 3117 - 3123. [Abstract] [Full Text] [PDF]
|
|