Hypertension. 2002;39:10-15
doi: 10.1161/hy0102.099031
doi: 10.1161/hy0102.099031
(Hypertension. 2002;39:10.)
© 2002 American Heart Association, Inc.
Scientific Contributions |
Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients
A Longitudinal Study
From the Department of Pharmacology and INSERM EMI 0107, Hôpital Européen Georges Pompidou (P.B., A.I.T., I.G., P.L., S.L.); Institut de Formation et de Recherche Cardiovasculaire (R.A.); and INSERM U 258, IPC Center (A.B.), Paris, France.
Correspondence to Professeur Stéphane Laurent, Service de Pharmacologie, Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, 20 Rue Leblanc, 75908 Paris Cedex 15, France. E-mail stephane.laurent{at}egp.ap-hop-Paris.fr
Arterial stiffness may predict coronary heart disease beyond classic risk factors. In a longitudinal study, we assessed the predictive value of arterial stiffness on coronary heart disease in patients with essential hypertension and without known clinical cardiovascular disease. Aortic stiffness was determined from carotid-femoral pulse wave velocity at baseline in 1045 hypertensives. The risk assessment of coronary heart disease was made by calculating the Framingham risk score according to the categories of gender, age, blood pressure, cholesterol, diabetes, and smoking. Mean age at entry was 51 years, and mean follow-up was 5.7 years. Coronary events (fatal and nonfatal myocardial infarction, coronary revascularization, and angina pectoris) and all cardiovascular events served as outcome variables in Cox proportional-hazard regression models. Fifty-three coronary events and 97 total cardiovascular events occurred. In univariate analysis, the relative risk of follow-up coronary event or any cardiovascular event increased with increasing level of pulse wave velocity; for 1 SD, ie, 3.5 m/s, relatives risks were 1.42 (95% confidence interval [CI], 1.10 to 1.82; P<0.01) and 1.41 (95% CI, 1.17 to 1.70; P<0.001), respectively. Framingham score significantly predicted the occurrence of coronary and all cardiovascular events in this population (P<0.01 and P<0.0001, respectively). In multivariate analysis, pulse wave velocity remained significantly associated with the occurrence of coronary event after adjustment either of Framingham score (for 3.5 m/s: relative risk, 1.34; 95% CI, 1.01 to 1.79; P=0.039) or classic risk factors (for 3.5 m/s: relative risk, 1.39; 95% CI, 1.08 to 1.79; P=0.01). Parallel results were observed for all cardiovascular events. This study provides the first direct evidence in a longitudinal study that aortic stiffness is an independent predictor of primary coronary events in patients with essential hypertension.
Key Words: arterial stiffness • cardiovascular morbidity • cardiovascular mortality • coronary heart disease
This article has been cited by other articles:
 |
|
 |
|
  F. H. Messerli and G. S. Panjrath The J-curve between blood pressure and coronary artery disease or essential hypertension: exactly how essential? J. Am. Coll. Cardiol., November 10, 2009; 54(20): 1827 - 1834. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Galarraga, F. Khan, P. Kumar, T. Pullar, and J. J. F. Belch Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritis Rheumatology, November 1, 2009; 48(11): 1418 - 1423. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Sengstock, R. L. Sands, B. W. Gillespie, X. Zhang, M. Kiser, G. Eisele, P. Vaitkevicius, M. Kuhlmann, N. W. Levin, A. Hinderliter, et al. Dominance of traditional cardiovascular risk factors over renal function in predicting arterial stiffness in subjects with chronic kidney disease Nephrol. Dial. Transplant., October 23, 2009; (2009) gfp559v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. H. Kim, L. J. Bugaj, Y. J. Oh, T. J. Bivalacqua, S. Ryoo, K. G. Soucy, L. Santhanam, A. Webb, A. Camara, G. Sikka, et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats J Appl Physiol, October 1, 2009; 107(4): 1249 - 1257. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Kumagai, T. Kasai, M. Kato, R. Naito, K.-i. Maeno, S. Kasagi, F. Kawana, S. Ishiwata, and K. Narui Establishment of the Cardio-Ankle Vascular Index in Patients With Obstructive Sleep Apnea Chest, September 1, 2009; 136(3): 779 - 786. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Horinaka, A. Yabe, H. Yagi, K. Ishimura, H. Hara, T. Iemua, and H. Matsuoka Comparison of Atherosclerotic Indicators Between Cardio Ankle Vascular Index and Brachial Ankle Pulse Wave Velocity Angiology, August 1, 2009; 60(4): 468 - 476. [Abstract] [PDF]
|
|
|
|
 |
|
 M Wong, S P Oakley, L Young, B Y Jiang, A Wierzbicki, G Panayi, P Chowienczyk, and B Kirkham Infliximab improves vascular stiffness in patients with rheumatoid arthritis Ann Rheum Dis, August 1, 2009; 68(8): 1277 - 1284. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. P. Kuhl Hypertrophic cardiomyopathy, fibrosis, and aortic stiffness an unidentified association unraveled by magnetic resonance imaging. J. Am. Coll. Cardiol., July 14, 2009; 54(3): 263 - 264. [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Nilsson, P. Boutouyrie, and S. Laurent Vascular Aging: A Tale of EVA and ADAM in Cardiovascular Risk Assessment and Prevention Hypertension, July 1, 2009; 54(1): 3 - 10. [Full Text] [PDF]
|
|
|
|
 |
|
 M. Yaron, Y. Greenman, J. B Rosenfeld, E. Izkhakov, R. Limor, E. Osher, G. Shenkerman, K. Tordjman, and N. Stern Effect of testosterone replacement therapy on arterial stiffness in older hypogonadal men Eur. J. Endocrinol., May 1, 2009; 160(5): 839 - 846. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Garcia and G. S. Kassab Right coronary artery becomes stiffer with increase in elastin and collagen in right ventricular hypertrophy J Appl Physiol, April 1, 2009; 106(4): 1338 - 1346. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Rerkpattanapipat, R. B. D'Agostino Jr, K. M. Link, E. Shahar, J. A. Lima, D. A. Bluemke, S. Sinha, D. M. Herrington, and W. G. Hundley Location of Arterial Stiffening Differs in Those With Impaired Fasting Glucose Versus Diabetes: Implications for Left Ventricular Hypertrophy From the Multi-Ethnic Study of Atherosclerosis Diabetes, April 1, 2009; 58(4): 946 - 953. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Chirinos, S. S. Franklin, R. R. Townsend, and L. Raij Body Mass Index and Hypertension Hemodynamic Subtypes in the Adult US Population Arch Intern Med, March 23, 2009; 169(6): 580 - 586. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Antonini-Canterin, S. Carerj, V. Di Bello, G. Di Salvo, S. La Carrubba, O. Vriz, D. Pavan, A. Balbarini, G. L. Nicolosi, and On behalf of the Research Group of the Italian Soc Arterial stiffness and ventricular stiffness: a couple of diseases or a coupling disease? A review from the cardiologist's point of view Eur J Echocardiogr, January 1, 2009; 10(1): 36 - 43. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. MacNee, J. Maclay, and D. McAllister Cardiovascular Injury and Repair in Chronic Obstructive Pulmonary Disease Proceedings of the ATS, December 1, 2008; 5(8): 824 - 833. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. H.G. Henskens, A. A. Kroon, R. J. van Oostenbrugge, E. H.B.M. Gronenschild, M. M.J.J. Fuss-Lejeune, P. A.M. Hofman, J. Lodder, and P. W. de Leeuw Increased Aortic Pulse Wave Velocity Is Associated With Silent Cerebral Small-Vessel Disease in Hypertensive Patients Hypertension, December 1, 2008; 52(6): 1120 - 1126. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Forst, B. Wilhelm, A. Pfutzner, W. Fuchs, U. Lehmann, F. Schaper, M. Weber, J. Muller, T. Konrad, and M. Hanefeld Investigation of the vascular and pleiotropic effects of atorvastatin and pioglitazone in a population at high cardiovascular risk Diabetes and Vascular Disease Research, November 1, 2008; 5(4): 298 - 303. [Abstract] [PDF]
|
|
|
|
|
|
C. Giannattasio, P. Salvi, F. Valbusa, A. Kearney-Schwartz, A. Capra, M. Amigoni, M. Failla, L. Boffi, F. Madotto, A. Benetos, et al. Simultaneous Measurement of Beat-to-Beat Carotid Diameter and Pressure Changes to Assess Arterial Mechanical Properties Hypertension, November 1, 2008; 52(5): 896 - 902. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Allison, J. E. Manson, R. D. Langer, A. Aragaki, S. Smoller, C. E. Lewis, A. Thomas, W. Lawson, B. B. Cochrane, J. Hsia, et al. Association Between Different Measures of Blood Pressure and Coronary Artery Calcium in Postmenopausal Women Hypertension, November 1, 2008; 52(5): 833 - 840. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q. Fu, W. Vongpatanasin, and B. D. Levine Neural and Nonneural Mechanisms for Sex Differences in Elderly Hypertension: Can Exercise Training Help? Hypertension, November 1, 2008; 52(5): 787 - 794. [Full Text] [PDF]
|
|
|
|
|
|
I. Wakabayashi and H. Masuda Relationships Between Vascular Indexes and Atherosclerotic Risk Factors in Patients With Type 2 Diabetes Mellitus Angiology, October 1, 2008; 59(5): 567 - 573. [Abstract] [PDF]
|
|
|
|
|
|
I. Nakae, S. Matsuo, T. Matsumoto, K. Mitsunami, and M. Horie Augmentation Index and Pulse Wave Velocity as Indicators of Cardiovascular Stiffness Angiology, August 1, 2008; 59(4): 421 - 426. [Abstract] [PDF]
|
|
|
|
|
|
S. Mathieu, H. Joly, G. Baron, A. Tournadre, J.-J. Dubost, J.-M. Ristori, J.-R. Lusson, and M. Soubrier Trend towards increased arterial stiffness or intima-media thickness in ankylosing spondylitis patients without clinically evident cardiovascular disease Rheumatology, August 1, 2008; 47(8): 1203 - 1207. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. G. Ruitenbeek, T. J.M. van der Cammen, A. H. van den Meiracker, and F. U.S. Mattace-Raso Age and Blood Pressure Levels Modify the Functional Properties of Central but Not Peripheral Arteries Angiology, July 1, 2008; 59(3): 290 - 295. [Abstract] [PDF]
|
|
|
|
 |
|
 M. Rakobowchuk, S. Tanguay, K. A. Burgomaster, K. R. Howarth, M. J. Gibala, and M. J. MacDonald Sprint interval and traditional endurance training induce similar improvements in peripheral arterial stiffness and flow-mediated dilation in healthy humans Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2008; 295(1): R236 - R242. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Steeghs, H. Gelderblom, J. o. t Roodt, O. Christensen, P. Rajagopalan, M. Hovens, H. Putter, T. J. Rabelink, and E. de Koning Hypertension and Rarefaction during Treatment with Telatinib, a Small Molecule Angiogenesis Inhibitor Clin. Cancer Res., June 1, 2008; 14(11): 3470 - 3476. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Orr, C. L. Gentile, B. M. Davy, and K. P. Davy Large Artery Stiffening With Weight Gain in Humans: Role of Visceral Fat Accumulation Hypertension, June 1, 2008; 51(6): 1519 - 1524. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Delahousse, M. Chaignon, L. Mesnard, P. Boutouyrie, M. E. Safar, T. Lebret, M. Pastural-Thaunat, L. Tricot, A. Kolko-Labadens, A. Karras, et al. Aortic Stiffness of Kidney Transplant Recipients Correlates with Donor Age J. Am. Soc. Nephrol., April 1, 2008; 19(4): 798 - 805. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Celik, S. Kaplan, R. Yilmaz, T. Erdogan, and A. Kiris Relationship Between Aortic Stiffness and the Development of Coronary Collateral in Patients With Coronary Artery Disease Angiology, January 1, 2008; 58(6): 671 - 676. [Abstract] [PDF]
|
|
|
|
 |
|
 D. A. McAllister, J. D. Maclay, N. L. Mills, G. Mair, J. Miller, D. Anderson, D. E. Newby, J. T. Murchison, and W. MacNee Arterial Stiffness Is Independently Associated with Emphysema Severity in Patients with Chronic Obstructive Pulmonary Disease Am. J. Respir. Crit. Care Med., December 15, 2007; 176(12): 1208 - 1214. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Boos, D. A. Lane, M. Karpha, D. G. Beevers, R. Haynes, and G. Y. H. Lip Circulating Endothelial Cells, Arterial Stiffness, and Cardiovascular Risk Stratification in Hypertension Chest, November 1, 2007; 132(5): 1540 - 1547. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Zhang, J. G. Fletcher, T. J. Vrtiska, A. Manduca, J. L. Thompson, M. L. Raghavan, R. J. Wentz, and C. H. McCollough Large-Vessel Distensibility Measurement with Electrocardiographically Gated Multidetector CT: Phantom Study and Initial Experience Radiology, October 1, 2007; 245(1): 258 - 266. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Marre and A. Leye Effects of perindopril in hypertensive patients with or without type 2 diabetes mellitus, and with altered insulin sensitivity Diabetes and Vascular Disease Research, September 1, 2007; 4(3): 163 - 173. [Abstract] [PDF]
|
|
|
|
 |
|
 D. Jegger, R. F. da Silva, I. Lartaud, V. Gaillard, X. Jeanrenaud, M. Nasratullah, L. K. von Segesser, J. Atkinson, P. Segers, H. Tevaearai, et al. Effects of an aging vascular model on healthy and diseased hearts Am J Physiol Heart Circ Physiol, September 1, 2007; 293(3): H1334 - H1343. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Roman, R. B. Devereux, J. R. Kizer, E. T. Lee, J. M. Galloway, T. Ali, J. G. Umans, and B. V. Howard Central Pressure More Strongly Relates to Vascular Disease and Outcome Than Does Brachial Pressure: The Strong Heart Study Hypertension, July 1, 2007; 50(1): 197 - 203. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M.L. Wallace, Yasmin, C. M. McEniery, K. M. Maki-Petaja, A. D. Booth, J. R. Cockcroft, and I. B. Wilkinson Isolated Systolic Hypertension Is Characterized by Increased Aortic Stiffness and Endothelial Dysfunction Hypertension, July 1, 2007; 50(1): 228 - 233. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Sabit, C. E. Bolton, P. H. Edwards, R. J. Pettit, W. D. Evans, C. M. McEniery, I. B. Wilkinson, J. R. Cockcroft, and D. J. Shale Arterial Stiffness and Osteoporosis in Chronic Obstructive Pulmonary Disease Am. J. Respir. Crit. Care Med., June 15, 2007; 175(12): 1259 - 1265. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Authors/Task Force Members:, G. Mancia, G. De Backer, A. Dominiczak, R. Cifkova, R. Fagard, G. Germano, G. Grassi, A. M. Heagerty, S. E. Kjeldsen, et al. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) Eur. Heart J., June 11, 2007; (2007) ehm236v1. [Full Text] [PDF]
|
|
|
|
 |
|
 C. A. A. Hulsman, J. R. Vingerling, A. Hofman, J. C. M. Witteman, and P. T. V.M. de Jong Blood Pressure, Arterial Stiffness, and Open-angle Glaucoma: The Rotterdam Study Arch Ophthalmol, June 1, 2007; 125(6): 805 - 812. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Palmieri, R. Pini, and M. Chiara Cavallini Pulsology Reloaded: Commentary on Similar Effects of Treatment on Central and Brachial Blood Pressure in Older Hypertensive Subjects Hypertension, June 1, 2007; 49(6): 1210 - 1212. [Full Text] [PDF]
|
|
|
|
|
|
N. A. Jatoi, P. Jerrard-Dunne, J. Feely, and A. Mahmud Impact of Smoking and Smoking Cessation on Arterial Stiffness and Aortic Wave Reflection in Hypertension Hypertension, May 1, 2007; 49(5): 981 - 985. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. J. Kullo and A. R. Malik Arterial Ultrasonography and Tonometry as Adjuncts to Cardiovascular Risk Stratification J. Am. Coll. Cardiol., April 3, 2007; 49(13): 1413 - 1426. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. R. Khoshdel, S. L. Carney, B. R. Nair, and A. Gillies Better Management of Cardiovascular Diseases by Pulse Wave Velocity: Combining Clinical Practice with Clinical Research using Evidence-Based Medicine Clin. Med. Res., March 1, 2007; 5(1): 45 - 52. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Achimastos, S. P. Efstathiou, T. Christoforatos, T. N. Panagiotou, G. S. Stergiou, and T. D. Mountokalakis Arterial Stiffness: Determinants and Relationship to the Metabolic Syndrome Angiology, February 1, 2007; 58(1): 11 - 20. [Abstract] [PDF]
|
|
|
|
|
|
H.-M. Su, K.-T. Lee, C.-S. Chu, M.-Y. Lee, T.-H. Lin, W.-C. Voon, S.-H. Sheu, and W.-T. Lai Effects of Heart Rate on Brachial-Ankle Pulse Wave Velocity and Ankle-Brachial Pressure Index in Patients Without Significant Organic Heart Disease Angiology, February 1, 2007; 58(1): 67 - 74. [Abstract] [PDF]
|
|
|
|
|
|
A. Koudsi, J. Oldroyd, P. McElduff, M. Banerjee, A. Vyas, and J. K. Cruickshank Maternal and Neonatal Influences on, and Reproducibility of, Neonatal Aortic Pulse Wave Velocity Hypertension, January 1, 2007; 49(1): 225 - 231. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. S Kassab Biomechanics of the cardiovascular system: the aorta as an illustratory example J R Soc Interface, December 22, 2006; 3(11): 719 - 740. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. A Ajjan and P. J Grant Cardiovascular disease prevention in patients with type 2 diabetes: the role of oral anti-diabetic agents Diabetes and Vascular Disease Research, December 1, 2006; 3(3): 147 - 158. [Abstract] [PDF]
|
|
|
|
 |
|
 H. J. Teede, D. Giannopoulos, F. S. Dalais, J. Hodgson, and B. P. McGrath Randomised, Controlled, Cross-Over Trial of Soy Protein with Isoflavones on Blood Pressure and Arterial Function in Hypertensive Subjects J. Am. Coll. Nutr., December 1, 2006; 25(6): 533 - 540. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Laurent, J. Cockcroft, L. Van Bortel, P. Boutouyrie, C. Giannattasio, D. Hayoz, B. Pannier, C. Vlachopoulos, I. Wilkinson, H. Struijker-Boudier, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications Eur. Heart J., November 1, 2006; 27(21): 2588 - 2605. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Gugleta, A. Kochkorov, R. Katamay, C. Zawinka, J. Flammer, and S. Orgul On pulse-wave propagation in the ocular circulation. Invest. Ophthalmol. Vis. Sci., September 1, 2006; 47(9): 4019 - 4025. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Leoncini, E. Ratto, F. Viazzi, V. Vaccaro, A. Parodi, V. Falqui, N. Conti, C. Tomolillo, G. Deferrari, and R. Pontremoli Increased Ambulatory Arterial Stiffness Index Is Associated With Target Organ Damage in Primary Hypertension Hypertension, September 1, 2006; 48(3): 397 - 403. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Stewart, B. Jiang, S. C. Millasseau, J. M. Ritter, and P. J. Chowienczyk Acute Reduction of Blood Pressure by Nitroglycerin Does Not Normalize Large Artery Stiffness in Essential Hypertension Hypertension, September 1, 2006; 48(3): 404 - 410. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. F. O'Rourke and J. B. Seward Central Arterial Pressure and Arterial Pressure Pulse: New Views Entering the Second Century After Korotkov Mayo Clin. Proc., August 1, 2006; 81(8): 1057 - 1068. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.-I. Tropeano, P. Boutouyrie, B. Pannier, R. Joannides, E. Balkestein, S. Katsahian, B. Laloux, C. Thuillez, H. Struijker-Boudier, and S. Laurent Brachial Pressure-Independent Reduction in Carotid Stiffness After Long-Term Angiotensin-Converting Enzyme Inhibition in Diabetic Hypertensives Hypertension, July 1, 2006; 48(1): 80 - 86. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D Fukuda, M Yoshiyama, K Shimada, H Yamashita, S Ehara, Y Nakamura, K Kamimori, A Tanaka, T Kawarabayashi, and J Yoshikawa Relation between aortic stiffness and coronary flow reserve in patients with coronary artery disease Heart, June 1, 2006; 92(6): 759 - 762. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B Jani and C Rajkumar Ageing and vascular ageing. Postgrad. Med. J., June 1, 2006; 82(968): 357 - 362. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. F. Ng, F. Fantin, C. Ng, F. Dockery, R. Schiff, K. A. Davies, C. Rajkumar, and J. C. Mason Takayasu's arteritis: a cause of prolonged arterial stiffness Rheumatology, June 1, 2006; 45(6): 741 - 745. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. S. Vasan Biomarkers of Cardiovascular Disease: Molecular Basis and Practical Considerations Circulation, May 16, 2006; 113(19): 2335 - 2362. [Full Text] [PDF]
|
|
|
|
|
|
Yasmin, I. B. Wilkinson, K. M. O'Shaughnessy, T. Lanne, R. De Basso, and J. T. Powell Influence of fibrillin-1 genotype on aortic stiffness in men: a note of caution J Appl Physiol, April 1, 2006; 100(4): 1431 - 1432. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. M. Dart, C. D. Gatzka, B. A. Kingwell, K. Willson, J. D. Cameron, Y.-L. Liang, K. L. Berry, L. M.H. Wing, C. M. Reid, P. Ryan, et al. Brachial Blood Pressure But Not Carotid Arterial Waveforms Predict Cardiovascular Events in Elderly Female Hypertensives Hypertension, April 1, 2006; 47(4): 785 - 790. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Paini, P. Boutouyrie, D. Calvet, A.-I. Tropeano, B. Laloux, and S. Laurent Carotid and Aortic Stiffness: Determinants of Discrepancies Hypertension, March 1, 2006; 47(3): 371 - 376. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Willum Hansen, J. A. Staessen, C. Torp-Pedersen, S. Rasmussen, L. Thijs, H. Ibsen, and J. Jeppesen Prognostic Value of Aortic Pulse Wave Velocity as Index of Arterial Stiffness in the General Population Circulation, February 7, 2006; 113(5): 664 - 670. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. H. Leung, I. T. Meredith, and J. D. Cameron Aortic stiffness affects the coronary blood flow response to percutaneous coronary intervention Am J Physiol Heart Circ Physiol, February 1, 2006; 290(2): H624 - H630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kisters, B. Gremmler, M. Hausberg, and S. Laurent Magnesium and Arterial Stiffness * Response Hypertension, February 1, 2006; 47(2): e3 - e3. [Full Text] [PDF]
|
|
|
|
|
|
T. Weber, J. Auer, M. F. O'Rourke, E. Kvas, E. Lassnig, G. Lamm, N. Stark, M. Rammer, and B. Eber Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions Eur. Heart J., December 2, 2005; 26(24): 2657 - 2663. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Hope, D. B. Tay, I. T. Meredith, and J. D. Cameron Waveform dispersion, not reflection, may be the major determinant of aortic pressure wave morphology Am J Physiol Heart Circ Physiol, December 1, 2005; 289(6): H2497 - H2502. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S.-H. H. Juo, T. Rundek, H.-F. Lin, R. Cheng, M.-Y. Lan, J. S. Huang, B. Boden-Albala, and R. L. Sacco Heritability of Carotid Artery Distensibility in Hispanics: The Northern Manhattan Family Study Stroke, November 1, 2005; 36(11): 2357 - 2361. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F.A. Sayed-Tabatabaei, M.J.E. van Rijn, A.F.C. Schut, Y.S. Aulchenko, E.A. Croes, M.C. Zillikens, H.A.P. Pols, J.C.M. Witteman, B.A. Oostra, and C.M. van Duijn Heritability of the Function and Structure of the Arterial Wall: Findings of the Erasmus Rucphen Family (ERF) Study Stroke, November 1, 2005; 36(11): 2351 - 2356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Van Doornum, G. McColl, and I. P. Wicks Tumour necrosis factor antagonists improve disease activity but not arterial stiffness in rheumatoid arthritis Rheumatology, November 1, 2005; 44(11): 1428 - 1432. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Natoli, T. L. Medley, A. A. Ahimastos, B. G. Drew, D. J. Thearle, R. J. Dilley, and B. A. Kingwell Sex Steroids Modulate Human Aortic Smooth Muscle Cell Matrix Protein Deposition and Matrix Metalloproteinase Expression Hypertension, November 1, 2005; 46(5): 1129 - 1134. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Meyer, B. P. McGrath, and H. J. Teede Overweight Women with Polycystic Ovary Syndrome Have Evidence of Subclinical Cardiovascular Disease J. Clin. Endocrinol. Metab., October 1, 2005; 90(10): 5711 - 5716. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J A Vita Endothelial function and clinical outcome Heart, October 1, 2005; 91(10): 1278 - 1279. [Full Text] [PDF]
|
|
|
|
|
|
J. T. Powell, R. J. Turner, M. Sian, R. Debasso, and T. Lanne Influence of fibrillin-1 genotype on the aortic stiffness in men J Appl Physiol, September 1, 2005; 99(3): 1036 - 1040. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. R. Sankatsing, S. W. Fouchier, S. de Haan, B. A. Hutten, E. de Groot, J. J.P. Kastelein, and E. S.G. Stroes Hepatic and Cardiovascular Consequences of Familial Hypobetalipoproteinemia Arterioscler Thromb Vasc Biol, September 1, 2005; 25(9): 1979 - 1984. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Williams, B. A Kingwell, K. Burke, J. McPherson, and A. M Dart Folic acid supplementation for 3 wk reduces pulse pressure and large artery stiffness independent of MTHFR genotype Am. J. Clinical Nutrition, July 1, 2005; 82(1): 26 - 31. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. N. Cohn, D. A. Duprez, and G. A. Grandits Arterial Elasticity as Part of a Comprehensive Assessment of Cardiovascular Risk and Drug Treatment Hypertension, July 1, 2005; 46(1): 217 - 220. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Bellien, R. Joannides, M. Iacob, P. Arnaud, and C. Thuillez Calcium-Activated Potassium Channels and NO Regulate Human Peripheral Conduit Artery Mechanics Hypertension, July 1, 2005; 46(1): 210 - 216. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Roman, R. B. Devereux, J. E. Schwartz, M. D. Lockshin, S. A. Paget, A. Davis, M. K. Crow, L. Sammaritano, D. M. Levine, B.-A. Shankar, et al. Arterial Stiffness in Chronic Inflammatory Diseases Hypertension, July 1, 2005; 46(1): 194 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. F. O'Rourke and M. E. Safar Relationship Between Aortic Stiffening and Microvascular Disease in Brain and Kidney: Cause and Logic of Therapy Hypertension, July 1, 2005; 46(1): 200 - 204. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Dijk, A. Algra, Y. van der Graaf, D. E. Grobbee, M. L. Bots, and on behalf of the SMART study group Carotid stiffness and the risk of new vascular events in patients with manifest cardiovascular disease. The SMART study Eur. Heart J., June 2, 2005; 26(12): 1213 - 1220. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Laurent Arterial stiffness: intermediate or surrogate endpoint for cardiovascular events? Eur. Heart J., June 2, 2005; 26(12): 1152 - 1154. [Full Text] [PDF]
|
|
|
|
|
|
A. E. DeVan, M. M. Anton, J. N. Cook, D. B. Neidre, M. Y. Cortez-Cooper, and H. Tanaka Acute effects of resistance exercise on arterial compliance J Appl Physiol, June 1, 2005; 98(6): 2287 - 2291. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Laurent, P. Boutouyrie, and P. Lacolley Structural and Genetic Bases of Arterial Stiffness Hypertension, June 1, 2005; 45(6): 1050 - 1055. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Fujiwara, P. H. M. Chaves, R. Takahashi, H. Amano, H. Yoshida, S. Kumagai, K. Fujita, D. G. Wang, and S. Shinkai Arterial Pulse Wave Velocity as a Marker of Poor Cognitive Function in an Elderly Community-Dwelling Population J. Gerontol. A Biol. Sci. Med. Sci., May 1, 2005; 60(5): 607 - 612. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D A Stakos, D P Schuster, E A Sparks, C F Wooley, K Osei, and H Boudoulas Long term cardiovascular effects of oral antidiabetic agents in non-diabetic patients with insulin resistance: double blind, prospective, randomised study Heart, May 1, 2005; 91(5): 589 - 594. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Sengstock, P. V. Vaitkevicius, and M. A. Supiano Arterial Stiffness Is Related to Insulin Resistance in Nondiabetic Hypertensive Older Adults J. Clin. Endocrinol. Metab., May 1, 2005; 90(5): 2823 - 2827. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. H. Dao, R. Essalihi, C. Bouvet, and P. Moreau Evolution and modulation of age-related medial elastocalcinosis: Impact on large artery stiffness and isolated systolic hypertension Cardiovasc Res, May 1, 2005; 66(2): 307 - 317. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Chirinos, J. P. Zambrano, S. Chakko, A. Veerani, A. Schob, H. J. Willens, G. Perez, and A. J. Mendez Aortic Pressure Augmentation Predicts Adverse Cardiovascular Events in Patients With Established Coronary Artery Disease Hypertension, May 1, 2005; 45(5): 980 - 985. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Senzaki, C.-H. Chen, H. Ishido, S. Masutani, T. Matsunaga, M. Taketazu, T. Kobayashi, N. Sasaki, S. Kyo, and Y. Yokote Arterial Hemodynamics in Patients After Kawasaki Disease Circulation, April 26, 2005; 111(16): 2119 - 2125. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Pannier, A. P. Guerin, S. J. Marchais, M. E. Safar, and G. M. London Stiffness of Capacitive and Conduit Arteries: Prognostic Significance for End-Stage Renal Disease Patients Hypertension, April 1, 2005; 45(4): 592 - 596. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Dernellis and M. Panaretou Aortic Stiffness Is an Independent Predictor of Progression to Hypertension in Nonhypertensive Subjects Hypertension, March 1, 2005; 45(3): 426 - 431. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. C. Millasseau, A. D. Stewart, S. J. Patel, S. R. Redwood, and P. J. Chowienczyk Evaluation of Carotid-Femoral Pulse Wave Velocity: Influence of Timing Algorithm and Heart Rate Hypertension, February 1, 2005; 45(2): 222 - 226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Van Doornum, G McColl, and I P Wicks Atorvastatin reduces arterial stiffness in patients with rheumatoid arthritis Ann Rheum Dis, December 1, 2004; 63(12): 1571 - 1575. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Lu, A. Pandit, and G. S. Kassab Biaxial incremental homeostatic elastic moduli of coronary artery: two-layer model Am J Physiol Heart Circ Physiol, October 1, 2004; 287(4): H1663 - H1669. [Abstract] [Full Text] [PDF]
|
|