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(Hypertension. 2007;50:152.)
© 2007 American Heart Association, Inc.

Introduction to the Sixth International Workshop on Structure and Function of the Vascular System

Harry A. Struijker-Boudier; Bernard I. Levy; Michel E. Safar

From the Department of Pharmacology and Toxicology, Faculty of Health, Medicine and Life Sciences (H.A.S.-B.), Universiteit Maastricht, The Netherlands; the Cardiovascular Research Center (B.I.L.), U689-INSERM, Hôpital Lariboisière, and Centre de Diagnostic (M.E.S.), Hôpital Hôtel-Dieu, Paris, France.

Correspondence to Prof Dr Harry A.J. Struijker-Boudier, Department of Pharmacology and Toxicology, Faculty of HML, Universiteit Maastricht, P.O. Box 616, 6200 MD Maastricht, The Netherlands. E-mail h.struijkerboudier@farmaco.unimaas.nl

An extract of the first 250 words of the full text is provided, because this article has no abstract.

From February 1 through February 3, 2007, the Sixth International Workshop on Structure and Function of Arteries was held in Paris. As with preceding workshops in this series, the presentations and discussions were of outstanding quality. The organizers were particularly happy with the manuscripts that were submitted for publication in this issue of Hypertension. As with the preceding workshops, the proceedings are published in this journal after a thorough review process and editorial decisions by the Editor and Associate Editors of Hypertension. The impact of these workshops and their proceedings is evident. No less than 4 of the 50 most highly cited papers from Hypertension were published as part of the proceedings of previous workshops.

The Sixth Workshop differed in one important aspect from the previous workshops. The focus this time was not only on large arteries. It also included small arteries and the microcirculation. There were several good reasons to expand the scope in this direction. First of all, the microcirculation is the major location of peripheral vascular resistance. Because increased resistance is the major hemodynamic change in most forms of hypertension, the microcirculation is the logical site of vascular research in hypertension. It has become evident that the structure of the microcirculation determines the distribution of peripheral resistance. A combination of inward eutrophic remodeling of small arteries and rarefaction of arterioles and capillaries is now believed to maintain the increased vascular resistance in hypertension. The second reason to include small arteries and the microcirculation is the . . . [Full Text of this Article]

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