Published online before print September 10, 2007, doi: 10.1161/HYPERTENSIONAHA.107.092650
(Hypertension. 2007;50:854.)
© 2007 American Heart Association, Inc.
Original Articles |
Blood Pressure Control in Hispanics in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
From the HealthPartners Research Foundation (K.L.M.), Minneapolis, Minn; School of Public Health (L.B.P., C.E.F.), University of Texas Health Science Center, Houston; Bronx Nephrology Hypertension (M.A.H.), Bronx, NY; Research and Development Service, Memphis Veterans Affairs Medical Center (W.C.C.), Tenn; National Heart, Lung, and Blood Institute (P.T.E.), Bethesda, Md; Centro Cardiovascular de Caguas (P.J.C.), Caguas, Puerto Rico; Cleveland Clinic (D.G.V.), Ohio; NitroMed (R.C.), Lexington, Mass; Heart Disease Program, University of California at Irvine (N.D.W.); Case Western Reserve University (J.T.W.), Cleveland, Ohio; and Department of Epidemiology and Prevention, Wake Forest University School of Medicine (D.C.G.), Winston-Salem, NC.
Correspondence to Karen L. Margolis, HealthPartners Research Foundation PO Box 1524, Mailstop 21111R, Minneapolis, MN 55440-1524. E-mail Karen.L.Margolis{at}HealthPartners.com
Historically, blood pressure control in Hispanics has been considerably less than that of non-Hispanic whites and blacks. We compared determinants of blood pressure control among Hispanic white, Hispanic black, non-Hispanic white, and non-Hispanic black participants (N=32 642) during follow-up in a randomized, practice-based, active-controlled trial. Hispanic blacks and whites represented 3% and 16% of the cohort, respectively; 33% were non-Hispanic black and 48% were non-Hispanic white. Hispanics were less likely to be controlled (<140/90 mm Hg) at enrollment, but within 6 to 12 months of follow-up, Hispanics had a greater proportion <140/90 mm Hg compared with non-Hispanics. At 4 years of follow-up, blood pressure was controlled in 72% of Hispanic whites, 69% of Hispanic blacks, 67% of non-Hispanic whites, and 59% of non-Hispanic blacks. Compared with non-Hispanic whites, Hispanic whites had a 20% greater odds of achieving BP control by 2 years of follow-up (odds ratio: 1.20; 95% CI: 1.10 to 1.31) after controlling for demographic variables and comorbidities, Hispanic blacks had a similar odds of achieving BP control (odds ratio: 1.04; 95% CI: 0.86 to 1.25), and non-Hispanic blacks had a 27% lower odds (odds ratio: 0.73; 95% CI: 0.69 to 0.78). We conclude that in all patients high levels of blood pressure control can be achieved with commonly available medications and that Hispanic ethnicity is not associated with inferior control in the setting of a clinical trial in which hypertensive patients had equal access to medical care, and medication was provided at no cost.
Key Words: hypertension • Hispanic • ethnicity • race • clinical trials • blood pressure control
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