Genetic, Association Studies

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Genomics and Precision Medicine for Clinicians and Scientists in Hypertension
Anna Dominiczak, Christian Delles and Sandosh Padmanabhan

Hypertension. 2017;69:e10-e13, originally published February 13, 2017
https://doi.org/10.1161/HYPERTENSIONAHA.116.08252

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Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to HydrochlorothiazideNovelty and Significance
Erika Salvi, Zhiying Wang, Federica Rizzi, Yan Gong, Caitrin W. McDonough, Sandosh Padmanabhan, Timo P. Hiltunen, Chiara Lanzani, Roberta Zaninello, Martina Chittani, Kent R. Bailey, Antti-Pekka Sarin, Matteo Barcella, Olle Melander, Arlene B. Chapman, Paolo Manunta, Kimmo K. Kontula, Nicola Glorioso, Daniele Cusi, Anna F. Dominiczak, Julie A. Johnson, Cristina Barlassina, Eric Boerwinkle, Rhonda M. Cooper-DeHoff and Stephen T. Turner

Hypertension. 2017;69:51-59, originally published October 31, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.116.08267

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Diurnal Blood Pressure Rhythmicity in Relation to Environmental and Genetic Cues in Untreated Referred PatientsNovelty and Significance
Chang-Sheng Sheng, Yi-Bang Cheng, Fang-Fei Wei, Wen-Yi Yang, Qian-Hui Guo, Fei-Ka Li, Qi-Fang Huang, Lutgarde Thijs, Jan A. Staessen, Ji-Guang Wang and Yan Li

Hypertension. 2017;69:128-135, originally published November 7, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.116.07958

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Associations Between Fetal Imprinted Genes and Maternal Blood Pressure in PregnancyNovelty and Significance
Clive J. Petry, Nuria Sanz Marcos, Gracielle Pimentel, M. Geoffrey Hayes, Michael Nodzenski, Denise M. Scholtens, Ieuan A. Hughes, Carlo L. Acerini, Ken K. Ong, William L. Lowe and David B. Dunger

Hypertension. 2016;68:1459-1466, originally published October 24, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.116.08261

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A Genetic Response Score for Hydrochlorothiazide UseNovelty and SignificanceInsights From Genomics and Metabolomics Integration
Mohamed H. Shahin, Yan Gong, Caitrin W. McDonough, Daniel M. Rotroff, Amber L Beitelshees, Timothy J. Garrett, John G. Gums, Alison Motsinger-Reif, Arlene B. Chapman, Stephen T. Turner, Eric Boerwinkle, Reginald F. Frye, Oliver Fiehn, Rhonda M. Cooper-DeHoff, Rima Kaddurah-Daouk and Julie A. Johnson

Hypertension. 2016;68:621-629, originally published July 5, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.116.07328

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Genome-Wide Gene–Sodium Interaction Analyses on Blood PressureNovelty and SignificanceThe Genetic Epidemiology Network of Salt-Sensitivity Study
Changwei Li, Jiang He, Jing Chen, Jinying Zhao, Dongfeng Gu, James E. Hixson, Dabeeru C. Rao, Cashell E. Jaquish, Charles C. Gu, Jichun Chen, Jianfeng Huang, Shufeng Chen and Tanika N. Kelly

Hypertension. 2016;68:348-355, originally published June 6, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.115.06765

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KCNK3 Variants Are Associated With Hyperaldosteronism and HypertensionNovelty and Significance
Ani Manichaikul, Stephen S. Rich, Matthew A. Allison, Nick A. Guagliardo, Douglas A. Bayliss, Robert M. Carey and Paula Q. Barrett

Hypertension. 2016;68:356-364, originally published June 13, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.116.07564

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Catestatin Gly364Ser Variant Alters Systemic Blood Pressure and the Risk for Hypertension in Human Populations via Endothelial Nitric Oxide Pathway
Malapaka Kiranmayi, Venkat R. Chirasani, Prasanna K.R. Allu, Lakshmi Subramanian, Elizabeth E. Martelli, Bhavani S. Sahu, Durairajpandian Vishnuprabu, Rathnakumar Kumaragurubaran, Saurabh Sharma, Dhanasekaran Bodhini, Madhulika Dixit, Arasambattu K. Munirajan, Madhu Khullar, Venkatesan Radha, Viswanathan Mohan, Ajit S. Mullasari, Sathyamangla V. Naga Prasad, Sanjib Senapati and Nitish R. Mahapatra

Hypertension. 2016;68:334-347, originally published June 20, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.116.06568

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Common Polymorphisms at the CYP17A1 Locus Associate With Steroid PhenotypeNovelty and SignificanceSupport for Blood Pressure Genome-Wide Association Study Signals at This Locus
Louise A. Diver, Scott M. MacKenzie, Robert Fraser, Frances McManus, E. Marie Freel, Samantha Alvarez-Madrazo, John D. McClure, Elaine C. Friel, Neil A. Hanley, Anna F. Dominiczak, Mark J. Caulfield, Patricia B. Munroe, John M. Connell and Eleanor Davies

Hypertension. 2016;67:724-732, originally published February 22, 2016
https://doi.org/10.1161/HYPERTENSIONAHA.115.06925

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Socioeconomic Position, But Not African Genomic Ancestry, Is Associated With Blood Pressure in the Bambui-Epigen (Brazil) Cohort Study of AgingNovelty and Significance
M. Fernanda Lima-Costa, Juliana Vaz de Mello Mambrini, Maria Lea Corrêa Leite, Sérgio Viana Peixoto, Josélia Oliveira Araújo Firmo, Antônio Ignácio de Loyola Filho, Mateus H. Gouveia, Thiago P. Leal, Alexandre Costa Pereira, James Macinko and Eduardo Tarazona-Santos

Hypertension. 2016;67:349-355, originally published December 28, 2015
https://doi.org/10.1161/HYPERTENSIONAHA.115.06609

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