The Second Five Years
As published last month in Hypertension, the editors, supported by our editorial board, have decided that one way the journal could feature a celebration of the 20th anniversary of Hypertension would be to identify not only each of the previous editors and associate editors of the journal, but also the outstanding manuscripts which were published in each of the five- year periods. In highlighting which manuscripts had the greatest impact on the hypertension research community, we were able to identify, through the help of the Lippincott William & Wilkins staff and the Institute for Scientific Information, the top 25 manuscripts in Hypertension that received the greatest impact in world literature. The first five-year period of the journal, edited by Dr Harriet Dustan and her staff, was featured last month. This month we honor Dr Edgar Haber and his colleagues: Drs Victor J. Dzau, Robert M. Graham, and Randall M. Zusman from Harvard University in Boston. During this five-year period, the journal doubled its publications moving from a journal published every other month to a monthly journal. Therefore, the identification of the top 25 manuscripts for this five- year period and the subsequent five- year periods are even more selective in their impact because twice as many papers were published in these five- year periods than during the first five years of Hypertension.
Thus, under Dr Haber’s able leadership from 1984–1988, Hypertension established its major academic position in the hypertension research area. During the latter years of his editorship, Dr Haber moved from Harvard University to a new position of responsibility as President of the Bristol- Meyers Squibb Research Institute. Therefore, much of the editorial responsibilities were assumed by Drs Dzau, Graham, and Zusman. To these individuals, we are all indebted for maintaining the excellence of the journal during this tenure (their photos are featured this month on the cover of the journal).
The following are the top 25 papers published in Hypertension between 1984–1988 according to their frequency of reference in the literature (in alphabetical order).
1. Alexander RW, Brock TA, Gimbrone MA Jr, Rittenhouse SE. Angiotensin increases inositol trisphophate and calcium in vascular smooth muscle. Hypertension. 1985;7(pt 1):447–451.
2. Blaustein MP. Sodium transport and hypertension: Where are we going? Hypertension. 1984;6:445–453.
3. Crozier IG, Nicholls MG, Ikram H, Espiner EA, Yandle TG, Jans S. Atrial natriuretic peptide in humans: production and clearance by various tissues. Hypertension. 1986;8(pt 2):II-11–II-15.
4. Day ML, Schwartz D, Wiegrand RC, Stockman PT, Brunnert SR, Tolunay HE, Currie MG, Standaert DG, Needleman P. Ventricular atriopeptin: unmasking of messenger RNA and peptide synthesis by hypertrophy or dexamethasone. Hypertension. 1987;9:485–491.
5. Dzau VJ. Significance of the vascular renin-angiotensin pathway. Hypertension. 1986;8:553–559.
6. Esler M, Jennings G, Korner P, Willett I, Dudley F, Hasking G, Anderson W, Lambert G. Assessment of human synpathetic nervous system activity from measurements of norepinephrine turnover. Hypertension. 1988;11:3–20.
7. Gryglewski RJ, Botting RM, Vane JR. Mediators produced by the endothelial cell. Hypertension. 1988;12:530–548.
8. Kleinert HD, Maack T, Atlas SA, Januszewicz A, Sealey JE, Laragh JH. Atrial natriuretic factor inhibits angiotensin-, norepinephrine-, and potassium-induced vascular contractility. Hypertension. 1984;6(pt 2):I-143–I-147.
9. Lockette W, Otsuka Y, Carretero O. The loss of endothelium-dependent vascular relaxation in hypertension. Hypertension. 1986;8(Pt 2):II-61–II-66.
10. Lucas CP, Estigarribia JA, Darga LL, Reaven GM. Insulin and blood pressure in obesity. Hypertension. 1985;7:702–706.
11. Luscher TF, Vanhoutte PM. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension. 1986;8:344–348.
12. Luscher TF, Raij L, Vanhoutte PM. Endothelium-dependent vascular responses in normotensive and hypertensive Dahl rats. Hypertension. 1987;9:157–163.
13. Lynch KR, Simnad VI, Ben-Ari ET, Garrison JC. Localization of preangiotensinogen messenger RNA sequences in the rat brain. Hypertension. 1986;8:540–543.
14. MacGregor GA. Sodium is more important than calcium in essential hypertension. Hypertension. 1985;7:628–640.
15. McCarron DA. Is calcium more important than sodium in the pathogenesis of essential hypertension? Hypertension. 1985;7:607–627.
16. Moncada S, Palmer RM, Higgs EA. The discovery of nitric oxide as the endogenous nitrovasodilator. Hypertension. 1988;12:365–372.
17. Needleman P, Adams SP, Cole BR, Currie MG, Geller DM, Michener ML, Saper CB, Schwartz D, Standaert DG. Atriopeptins as cardiac hormones. Hypertension. 1985;7:469–482.
18. Nussberger J, Brunner DB, Waeber B, Brunner HR. True versus immunoreactive angiotensin II in human plasma. Hypertension. 1985;7(pt 2):I-1–I-7.
19. Okamura T, Miyazaki M, Inagami T, Toda N. Vascular renin-angiotensin system in two kidney, one-clip hypertensive rats. Hypertension. 1986;8:560–565.
20. Owens GK. Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats. Hypertension. 1987;9:178–187.
21. Pickering TG, Harshfield GA, Devereux RB, Laragh JH. What is the role of ambulatory blood pressure monitoring in the management of hypertensive patients? Hypertension. 1985;7:171–177.
22. Pohl U, Holtz J, Busse R, Bassenge E. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension. 1986;8:37–44.
23. Richards AM, Nicholls MG, Espiner EA, Ikram H, Yandle TG, Joyce SL, Cullens MM. Effects of alpha-human atrial natriuretic peptide in essential hypertension. Hypertension. 1985;7:812–817.
24. Singer P, Godicke W, Voigt S, Hajdu I, Weiss M. Postprandial hyperinsulinemia in patients with mild essential hypertension. Hypertension. 1985;7: 182–186.
25. Weinberger MH, Miller JZ, Luft FC, Grim CE, Fineberg NS. Definitions and characteristics of sodium sensitivity and blood pressure resistance. Hypertension. 1986;8(pt 2):II-127–II-134.