Fourth International Seminar on Cardiovascular Biology and Medicine
The articles that follow in this issue of Hypertension represent part of the proceedings of a special symposium, the Fourth International Seminar on Cardiovascular Biology and Medicine, on May 16 through 18, 2001. This program was organized by Prof Javier Díez in the context of a continuous medical education program of the Spanish Ministry of Health with a special unrestricted educational grant-in-aid from Hoffman-La Roche.
Prof Díez agreed to serve as Guest Editor and to work closely with the Editor-in-Chief at each step to ensure that no breach occurred with our agreed-upon administrative and editorial procedure for publication of the proceedings. Moreover, we agreed in advance to discuss all financial arrangements with the American Heart Association independent of journal editors.
The purpose of this seminar was to review current fundamental and clinical subjects dealing with hypertension and atherosclerosis that have not enjoyed sufficient attention. For this reason, the seminar dealt primarily with review topics. Each of the papers submitted for publication were subjected to the same peer review process that applies to all other manuscripts submitted to Hypertension. This peer review process involved the prior selection of referees well in advance of the meeting and, with agreement by the editor, the selection of all potential reviewers. Moreover, we agreed that those manuscripts that were accepted would be included in regular issues of the journal rather than in a special journal supplement. The seminar participants/authors came to the meeting with their manuscripts, which were then immediately forwarded to the reviewers. Those papers that passed the peer review process were sent to the editorial office for publication.
The seminar was organized according to the following topics: interactions between genes and environment and susceptibility to cardiovascular diseases, role of alterations of extracellular matrix in the development and progression of cardiac failure and renal insufficiency, contribution of oxidative stress to endothelial dysfunction and vascular inflammation in hypertension and atherosclerosis, regulation of cardiac cell death and regeneration in hypertensive heart disease and ischemic heart disease, and the impact of each of these areas on the diagnosis and treatment of cardiovascular patients. In this regard, a major effort was made to link clinical science with recent basic developments derived from genomics and molecular biology.
We hope that the readers of this journal will value these special review topics and that this material will stimulate further interest and research work in this area. Toward this end, we hope that these 2 issues of Hypertension will provide an important reference work on these respective topics.