Abstract 465: Evolution of Cardiovascular Lifestyle Behaviours Occurring in Hypercholesterolemic Patients Concomitantly to the Intake of Phytosterol-supplemented Yoghurt.
Objective: to assess the evolution of cardiovascular lifestyle behaviours in hypercholesterolemic patients occurring concomitantly with changes in their daily intake of phytosterol-supplemented yoghurt (Phyto-SY).
METHODS: Nationwide prospective observational study conducted in Spanish and French general practice Each GP proposed lifestyle modification to 5 consecutive patients presenting with hypercholesterolemia, (taking or not hypocholesterolemic drugs) and recommended daily consumption of Phyto-SY. Study design included an inclusion visit, a patient’s self-monitoring assessment after 1 month and a final end-visit after four months. Main evaluation criterion : nutritional lifestyle score. Secondary criteria: Total, LDL and HDL cholesterol, waist circumference, daily walking time.
Results: 2376 hypercholesterolemic patients, 56.2 years old ± 11.9 (women 54.8%) were included. Nutritional lifestyle score decreased from 15.4 ± 5.4 to 8.7± 4.0 (p<0,0001), either in never-treated patients (15.3 ± 5.4 to 8.6 ± 3.9; p<0,0001) or in patients treated with hypocholesterolemic drugs (15.5 ± 5.4 to 8.9 ± 4.1; p<0,0001). Total cholesterol decreased 10.6% (<0.0001), HDL-C increased 8.0% (<0.0001), and LDL-C decreased 12.7% (<0.0001). Frequency of walking (>30 min) increased from 59.3% to 78.3% (p<0.0001); by contrast overweight frequency decreased from 22.8% to 17.5% (p<0.0001) and waist circumference from 94.6 ± 13.3 cm to 93.0 ± 12.8 (p<0.0001).
Conclusion: Improvement in nutritional lifestyle score, involving regular consumption of Phyto-SY over 4 months was significantly linked to a healthier lifestyle and to beneficial modification of atherogenic lipid profile, thereby reflecting patient empowerment in a “real life” context.
- © 2012 by American Heart Association, Inc.