The article, “Ramipril reduces large-artery stiffness in peripheral arterial disease and promotes elastogenic remodeling in cell culture” by Ahimastos et al (Ahimastos AA, Natoli AK, Lawler A, Blombery PA, Kingwell BA) has been retracted. The article was published in Hypertension (2005;45:1194–1199. doi: 10.1161/01.HYP.0000168945.44069.aa) online on May 16, 2005 and in print in the June 2005 issue of the journal.
The authors wish to retract the above article based on inadequate validation of primary data sources and data misrepresentation. An independent review of the study data was conducted following an admission of scientific misconduct by the first author, Dr Ahimastos, related to another study in peripheral arterial disease (Ahimastos, JAMA, 309(5):453–460, 2013). This resulted in a decision by the authors to retract the article, although the retraction has not been signed by Dr Ahimastos, who maintains the integrity of the data and validity of results. The other authors were not involved in any misconduct and apologize unreservedly to the editors, reviewers, and readers of Hypertension. Given the current indications for ramipril, we do not believe that there has been any negative clinical impact on patients.
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