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Volume 42, Issue 4; October 1, 2003
Brief Reviews
Editorial Commentaries
Scientific Contributions
Hypertension Electronic Pages
Letters to the Editor
Preface
Awards
State of the Art Lectures
Corrections
Scientific Contributions, Part 2
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Brief Reviews
Is the Relation of Systolic Blood Pressure to Risk of Cardiovascular Disease Continuous and Graded, or Are There Critical Values?
William B. Kannel, Ramachandran S. Vasan, and Daniel Levy
Hypertension. 2003;42:453-456; published online before print September 15 2003, doi:10.1161/01.HYP.0000093382.69464.C4.
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Editorial Commentaries
Reproducibility of BP Responses to Changes in Dietary Salt: Compelling Evidence for Universal Sodium Restriction?
Brent M. Egan
Hypertension. 2003;42:457-458; published online before print August 25 2003, doi:10.1161/01.HYP.0000091272.24311.EF.
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Scientific Contributions
Individual Blood Pressure Responses to Changes in Salt Intake: Results From the DASH-Sodium Trial
Eva Obarzanek, Michael A. Proschan, William M. Vollmer, Thomas J. Moore, Frank M. Sacks, Lawrence J. Appel, Laura P. Svetkey, Marlene M. Most-Windhauser, and Jeffrey A. Cutler
Hypertension. 2003;42:459-467; published online before print September 2 2003, doi:10.1161/01.HYP.0000091267.39066.72.
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Measures of Obesity Are Associated With Vascular Stiffness in Young and Older Adults
Rachel P. Wildman, Rachel H. Mackey, Andrew Bostom, Trina Thompson, and Kim Sutton-Tyrrell
Hypertension. 2003;42:468-473; published online before print September 2 2003, doi:10.1161/01.HYP.0000090360.78539.CD.
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Serum Uric Acid and Plasma Norepinephrine Concentrations Predict Subsequent Weight Gain and Blood Pressure Elevation
Kazuko Masuo, Hideki Kawaguchi, Hiroshi Mikami, Toshio Ogihara, and Michael L. Tuck
Hypertension. 2003;42:474-480; published online before print September 2 2003, doi:10.1161/01.HYP.0000091371.53502.D3.
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Spontaneous Indices Are Inconsistent With Arterial Baroreflex Gain
Ruth D. Lipman, Julie K. Salisbury, and J. Andrew Taylor
Hypertension. 2003;42:481-487; published online before print September 15 2003, doi:10.1161/01.HYP.0000091370.83602.E6.
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Cardiovascular Responses Evoked by Leptin Acting on Neurons in the Ventromedial and Dorsomedial Hypothalamus
Ainsley J. Marsh, Marco A.P. Fontes, Suzanne Killinger, Dorota B. Pawlak, Jaimie W. Polson, and Roger A.L. Dampney
Hypertension. 2003;42:488-493; published online before print August 25 2003, doi:10.1161/01.HYP.0000090097.22678.0A.
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Endothelin-1 Gene LYS198ASN Polymorphism and Blood Pressure Reactivity
Frank A. Treiber, Paule Barbeau, Gregory Harshfield, Hyun-Sik Kang, David M. Pollock, Jennifer S. Pollock, and Harold Snieder
Hypertension. 2003;42:494-499; published online before print September 8 2003, doi:10.1161/01.HYP.0000091266.41333.15.
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Genetic Variants of Angiotensin II Receptors and Cardiovascular Risk in Hypertension
Alun Jones, Sukhbir S. Dhamrait, John R. Payne, Emma Hawe, Ping Li, Iqbal S. Toor, Le Luong, Peter T.E. Wootton, George J. Miller, Steve E. Humphries, and Hugh E. Montgomery
Hypertension. 2003;42:500-506; published online before print August 18 2003, doi:10.1161/01.HYP.0000088853.27673.D0.
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Physiological Impact of Increased Expression of the AT
1
Angiotensin Receptor
Thu H. Le, Hyung-Suk Kim, Andrew M. Allen, Robert F. Spurney, Oliver Smithies, and Thomas M. Coffman
Hypertension. 2003;42:507-514; published online before print September 8 2003, doi:10.1161/01.HYP.0000092000.07559.57.
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Comprehensive Congenic Coverage Revealing Multiple Blood Pressure Quantitative Trait Loci on Dahl Rat Chromosome 10
Ana Palijan, Raphaelle Lambert, Julie Dutil, Zsuzsa Sivo, and Alan Y. Deng
Hypertension. 2003;42:515-522; published online before print August 25 2003, doi:10.1161/01.HYP.0000090096.88509.15.
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Data Supplement
Hypertension in the (mRen-2)27 Rat Is Not Explained by Enhanced Kinetics of Transgenic Ren-2 Renin
Pei Rong, Duncan J. Campbell, and Sandford L. Skinner
Hypertension. 2003;42:523-527; published online before print September 29 2003, doi:10.1161/01.HYP.0000093383.18302.A7.
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Relation Between Left Ventricular Midwall Function and Coronary Vasodilator Capacity in Arterial Hypertension
Michaela Kozàkovà, Ele Ferrannini, and Carlo Palombo
Hypertension. 2003;42:528-533; published online before print September 2 2003, doi:10.1161/01.HYP.0000090120.22445.B0.
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Hypertensive Retinal Vessel Wall Signs in a General Older Population: The Blue Mountains Eye Study
Jie Jin Wang, Paul Mitchell, Harry Leung, Elena Rochtchina, Tien Yin Wong, and Ronald Klein
Hypertension. 2003;42:534-541; published online before print August 25 2003, doi:10.1161/01.HYP.0000090122.38230.41.
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Important Role of Nitric Oxide in the Effect of Angiotensin-Converting Enzyme Inhibitor Imidapril on Vascular Injury
Rui Chen, Masaru Iwai, Lan Wu, Jun Suzuki, Li-Juan Min, Tetsuya Shiuchi, Takashi Sugaya, Hong-Wei Liu, Tai-Xing Cui, and Masatsugu Horiuchi
Hypertension. 2003;42:542-547; published online before print September 8 2003, doi:10.1161/01.HYP.0000092440.52239.39.
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5,6-Epoxyeicosatrienoic Acid Mediates the Enhanced Renal Vasodilation to Arachidonic Acid in the SHR
Silvia I. Pomposiello, John Quilley, Mairead A. Carroll, John R. Falck, and John C. McGiff
Hypertension. 2003;42:548-554; published online before print August 25 2003, doi:10.1161/01.HYP.0000090095.87899.36.
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14,15-Epoxyeicosa-5(Z)-Enoic-mSI: A 14,15- and 5,6-EET Antagonist in Bovine Coronary Arteries
Kathryn M. Gauthier, Setti G. Jagadeesh, John R. Falck, and William B. Campbell
Hypertension. 2003;42:555-561; published online before print September 2 2003, doi:10.1161/01.HYP.0000091265.94045.C7.
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Aged Spontaneously Hypertensive Rats Exhibit a Selective Loss of EDHF-Mediated Relaxation in the Renal Artery
Eckhart Büssemaker, Rüdiger Popp, Beate Fisslthaler, Christiana M. Larson, Ingrid Fleming, Rudi Busse, and Ralf P. Brandes
Hypertension. 2003;42:562-568; published online before print August 18 2003, doi:10.1161/01.HYP.0000088852.28814.E2.
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Data Supplement
Insulin-Stimulated Hydrogen Peroxide Increases Guanylate Cyclase Activity in Vascular Smooth Muscle
Ming Yang, Yu Yang, Sui Zhang, and Andrew M. Kahn
Hypertension. 2003;42:569-573; published online before print September 8 2003, doi:10.1161/01.HYP.0000092441.27668.BD.
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Molecular Mechanisms of Inhibition of Vascular Growth by Angiotensin-(1-7)
E. Ann Tallant and Michelle A. Clark
Hypertension. 2003;42:574-579; published online before print September 2 2003, doi:10.1161/01.HYP.0000090322.55782.30.
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11ß-Hydroxysteroid Dehydrogenase Type 2 in Mouse Aorta: Localization and Influence on Response to Glucocorticoids
Clare Christy, Patrick W.F. Hadoke, Janice M. Paterson, John J. Mullins, Jonathan R. Seckl, and Brian R. Walker
Hypertension. 2003;42:580-587; published online before print August 18 2003, doi:10.1161/01.HYP.0000088855.06598.5B.
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Angiotensin IINAD(P)H OxidaseStimulated Superoxide Modifies Tubulovascular Nitric Oxide Cross-Talk in Renal Outer Medulla
Takefumi Mori and Allen W. Cowley, Jr
Hypertension. 2003;42:588-593; published online before print September 15 2003, doi:10.1161/01.HYP.0000091821.39824.09.
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Downregulation of Renal CYP-Derived Eicosanoid Synthesis in Rats With Diet-Induced Hypertension
Mong-Heng Wang, Anita Smith, Yiqiang Zhou, Hsin-Hsin Chang, Songbai Lin, Xueying Zhao, John D. Imig, and Anne M. Dorrance
Hypertension. 2003;42:594-599; published online before print August 25 2003, doi:10.1161/01.HYP.0000090123.55365.BA.
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Angiotensin AT
2
Receptors Directly Stimulate Renal Nitric Oxide in Bradykinin B
2
-ReceptorNull Mice
Peter M. Abadir, Robert M. Carey, and Helmy M. Siragy
Hypertension. 2003;42:600-604; published online before print September 2 2003, doi:10.1161/01.HYP.0000090323.58122.5C.
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Beneficial Effects of Antioxidant Vitamins on the Stenotic Kidney
Alejandro R. Chade, Martin Rodriguez-Porcel, Joerg Herrmann, James D. Krier, Xiangyang Zhu, Amir Lerman, and Lilach O. Lerman
Hypertension. 2003;42:605-612; published online before print August 18 2003, doi:10.1161/01.HYP.0000089880.32275.7C.
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Organ-Specific Overexpression of Renal LAT2 and Enhanced Tubular
L
-DOPA Uptake Precede the Onset of Hypertension
Maria João Pinho, Pedro Gomes, Maria Paula Serrão, Maria João Bonifácio, and Patrício Soares-da-Silva
Hypertension. 2003;42:613-618; published online before print September 15 2003, doi:10.1161/01.HYP.0000091822.00166.B1.
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Sampling Requirements for Ambulatory Blood Pressure Monitoring in the Diagnosis of Hypertension in Pregnancy
Ramón C. Hermida and Diana E. Ayala
Hypertension. 2003;42:619-624; published online before print August 25 2003, doi:10.1161/01.HYP.0000090124.38835.AA.
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Data Supplement
Hypertension Electronic Pages
Hypertension
Online Only: October 2003
John E. Hall
Hypertension. 2003;42:625.
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Letters to the Editor
Antioxidant Effect of Lercanidipine
Response
Brian Tomlinson, Iris F.F. Benzie, Stefano Taddei, Agostino Virdis, Lorenzo Ghiadoni, Daniele Versari, Guido Salvetti, Armando Magagna, and Antonio Salvetti
Hypertension. 2003;42:e10-e11; published online before print September 2 2003, doi:10.1161/01.HYP.0000091372.14174.89.
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Abstracts From the Eighth Annual Meeting of the European Council for Blood Pressure and Cardiovascular Research (ECCR)
Hypertension. 2003;42:626-648.
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Preface
Proceedings of the XVth Scientific Meeting of the Inter-American Society of Hypertension
Joey P. Granger
Hypertension. 2003;42:653; published online before print September 29 2003, doi:10.1161/01.HYP.0000094241.32778.40.
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Awards
New Investigator and Travel Awards
Hypertension. 2003;42:655.
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2003 IASH Lifetime Achievement Award
Hypertension. 2003;42:656; published online before print September 29 2003, doi:10.1161/01.HYP.0000094242.32778.9B.
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State of the Art Lectures
Hormone Replacement Therapy and Inflammation: Interactions in Cardiovascular Disease
Andrew P. Miller, Yiu-Fai Chen, Dongqi Xing, Wenguang Feng, and Suzanne Oparil
Hypertension. 2003;42:657-663; published online before print August 11 2003, doi:10.1161/01.HYP.0000085560.02979.0C.
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Peroxisome Proliferator-Activated Receptors: Vascular and Cardiac Effects in Hypertension
Ernesto L. Schiffrin, Farhad Amiri, Karim Benkirane, Marc Iglarz, and Quy N. Diep
Hypertension. 2003;42:664-668; published online before print July 21 2003, doi:10.1161/01.HYP.0000084370.74777.B6.
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Inhibitors of 20-HETE Formation Promote Salt-Sensitive Hypertension in Rats
Kimberly M. Hoagland, Averia K. Flasch, and Richard J. Roman
Hypertension. 2003;42:669-673; published online before print July 21 2003, doi:10.1161/01.HYP.0000084634.97353.1A.
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Corrections
Correction for vol. 42, p. 136
Hypertension. 2003;42:e12; published online before print September 2 2003, doi:10.1161/01.HYP.0000091974.13474.66.
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Scientific Contributions, Part 2
Gene Transfer of eNOS to the Thick Ascending Limb of eNOS-KO Mice Restores the Effects of
L
-Arginine on NaCl Absorption
Pablo A. Ortiz, Nancy J. Hong, Ding Wang, and Jeffrey L. Garvin
Hypertension. 2003;42:674-679; published online before print August 11 2003, doi:10.1161/01.HYP.0000085561.00001.81.
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Effects of Exogenous Heme on Renal Function: Role of Heme Oxygenase and Cyclooxygenase
Francisca Rodriguez, Rowena Kemp, Michael Balazy, and Alberto Nasjletti
Hypertension. 2003;42:680-684; published online before print August 4 2003, doi:10.1161/01.HYP.0000085785.40581.1A.
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ß2 Adrenoceptor Functional Gene Variants, Obesity, and Blood Pressure Level Interactions in the General Population
Alexandre C. Pereira, Marcilene S. Floriano, Glória F.A. Mota, Roberto S. Cunha, Fernando L. Herkenhoff, José G. Mill, and José E. Krieger
Hypertension. 2003;42:685-692; published online before print August 4 2003, doi:10.1161/01.HYP.0000085648.65419.17.
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N-Domain Angiotensin I-Converting Enzyme With 80 kDa as a Possible Genetic Marker of Hypertension
Georgia D.M. Marques, Beata M.R. Quinto, Frida L. Plavinik, José E. Krieger, Odair Marson, and Dulce E. Casarini
Hypertension. 2003;42:693-701; published online before print August 4 2003, doi:10.1161/01.HYP.0000085784.18572.CB.
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Contribution of Genetic Factors to Renal Lesions in the Stroke-Prone Spontaneously Hypertensive Rat
Bruna Gigante, Speranza Rubattu, Rosita Stanzione, Alessia Lombardi, Alfonso Baldi, Feliciano Baldi, and Massimo Volpe
Hypertension. 2003;42:702-706; published online before print July 21 2003, doi:10.1161/01.HYP.0000084635.01667.8A.
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Role of Endogenous Angiotensin II on Glutamatergic Actions in the Rostral Ventrolateral Medulla in Goldblatt Hypertensive Rats
Taís Helena F. Carvalho, Cássia T. Bergamaschi, Oswaldo U. Lopes, and Ruy R. Campos
Hypertension. 2003;42:707-712; published online before print August 11 2003, doi:10.1161/01.HYP.0000086524.35251.2D.
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Recovery of High Blood Pressure After Chronic Lesions of the Commissural NTS in SHR
Monica Akemi Sato, Gerhardus Hermanus Maria Schoorlemmer, José Vanderlei Menani, Oswaldo Ubríaco Lopes, and Eduardo Colombari
Hypertension. 2003;42:713-718; published online before print August 4 2003, doi:10.1161/01.HYP.0000086523.51029.EC.
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Blunted Fenfluramine-Evoked Prolactin Secretion in Hypertensive Rats
Sean D. Stocker, Matthew F. Muldoon, and Alan F. Sved
Hypertension. 2003;42:719-724; published online before print July 28 2003, doi:10.1161/01.HYP.0000082807.71659.4C.
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Sympathoexcitation by PVN-Injected Bicuculline Requires Activation of Excitatory Amino Acid Receptors
Qing Hui Chen, Joseph R. Haywood, and Glenn M. Toney
Hypertension. 2003;42:725-731; published online before print August 4 2003, doi:10.1161/01.HYP.0000085197.20043.44.
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Responses to GABA
A
Receptor Activation Are Altered in NTS Neurons Isolated From Renal-Wrap Hypertensive Rats
Gleb Tolstykh, Sergei Belugin, Olga Tolstykh, and Steve Mifflin
Hypertension. 2003;42:732-736; published online before print July 21 2003, doi:10.1161/01.HYP.0000084371.17927.02.
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Peroxisome Proliferator-Activated Receptor-
and Receptor-
Activators Prevent Cardiac Fibrosis in Mineralocorticoid-Dependent Hypertension
Marc Iglarz, Rhian M. Touyz, Emilie C. Viel, Pierre Paradis, Farhad Amiri, Quy N. Diep, and Ernesto L. Schiffrin
Hypertension. 2003;42:737-743; published online before print July 14 2003, doi:10.1161/01.HYP.0000083511.91817.B1.
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Pregnant Rats With 5/6 Nephrectomy Have Normal Volume Expansion Despite Lower Renin and Kallikrein
Sofía P. Salas, Andrea Giacaman, and Carlos P. Vío
Hypertension. 2003;42:744-748; published online before print August 4 2003, doi:10.1161/01.HYP.0000085783.96609.0C.
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Enhanced Renal Immunocytochemical Expression of ANG-(1-7) and ACE2 During Pregnancy
K. Bridget Brosnihan, Liomar A.A. Neves, JaNae Joyner, David B. Averill, Mark C. Chappell, Renu Sarao, Josef Penninger, and Carlos M. Ferrario
Hypertension. 2003;42:749-753; published online before print July 21 2003, doi:10.1161/01.HYP.0000085220.53285.11.
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Role of Angiotensin II and Reactive Oxygen Species in Cyclosporine ADependent Hypertension
Akira Nishiyama, Hiroyuki Kobori, Toshiki Fukui, Guo-Xing Zhang, Li Yao, Matlubur Rahman, Hirofumi Hitomi, Hideyasu Kiyomoto, Takatomi Shokoji, Shoji Kimura, Masakazu Kohno, and Youichi Abe
Hypertension. 2003;42:754-760; published online before print July 21 2003, doi:10.1161/01.HYP.0000085195.38870.44.
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Attenuated Responses to Angiotensin II in Follitropin Receptor Knockout Mice, a Model of Menopause-Associated Hypertension
Danesh Javeshghani, Rhian M. Touyz, M. Ram Sairam, Agostino Virdis, Mario Fritsch Neves, and Ernesto L. Schiffrin
Hypertension. 2003;42:761-767; published online before print July 28 2003, doi:10.1161/01.HYP.0000085331.22169.3F.
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Reduced Endothelial Vascular Relaxation in Growth-Restricted Offspring of Pregnant Rats With Reduced Uterine Perfusion
Jason A. Payne, Barbara T. Alexander, and Raouf A. Khalil
Hypertension. 2003;42:768-774; published online before print July 21 2003, doi:10.1161/01.HYP.0000084990.88147.0C.
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Salt-Sensitive Hypertension After Exposure to Angiotensin Is Associated With Inability to Upregulate Renal Epoxygenases
Xueying Zhao, David M. Pollock, Darryl C. Zeldin, and John D. Imig
Hypertension. 2003;42:775-780; published online before print August 4 2003, doi:10.1161/01.HYP.0000085649.28268.DF.
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Estrogen or the AT1 Antagonist Olmesartan Reverses the Development of Profound Hypertension in the Congenic mRen2.Lewis Rat
Mark C. Chappell, Patricia E. Gallagher, David B. Averill, Carlos M. Ferrario, and K. Bridget Brosnihan
Hypertension. 2003;42:781-786; published online before print July 21 2003, doi:10.1161/01.HYP.0000085210.66399.A3.
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Perturbation of D
1
Dopamine and AT
1
Receptor Interaction in Spontaneously Hypertensive Rats
Chunyu Zeng, Yingjin Luo, Laureano D. Asico, Ulrich Hopfer, Gilbert M. Eisner, Robin A. Felder, and Pedro A. Jose
Hypertension. 2003;42:787-792; published online before print August 4 2003, doi:10.1161/01.HYP.0000085334.34963.4E.
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Salt Appetite and the Renin-Angiotensin System: Effect of Oxytocin Deficiency
Katya Rigatto, Robert Puryear, Iveta Bernatova, and Mariana Morris
Hypertension. 2003;42:793-797; published online before print September 2 2003, doi:10.1161/01.HYP.0000090321.81218.7B.
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Low-Dose Angiotensin II Enhances Pressor Responses Without Causing Sustained Hypertension
Laura I. Pelaez, Melissa C. Manriquez, Karl A. Nath, Juan C. Romero, and Luis A. Juncos
Hypertension. 2003;42:798-801; published online before print July 21 2003, doi:10.1161/01.HYP.0000085782.99773.B6.
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SR141716A-Sensitive Enhancement of ET-1 Hypotensive Effect by Chronic NOS Inhibition
Hugo C.D. Souza, Helio C. Salgado, Gustavo Ballejo, and Maria Cristina O. Salgado
Hypertension. 2003;42:802-805; published online before print August 11 2003, doi:10.1161/01.HYP.0000088362.50484.4C.
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Role of Reactive Oxygen Species in Endothelin-Induced Hypertension
Mona H. Sedeek, Maria T. Llinas, Heather Drummond, Lourdes Fortepiani, Sean R. Abram, Barbara T. Alexander, Jane F. Reckelhoff, and Joey P. Granger
Hypertension. 2003;42:806-810; published online before print July 21 2003, doi:10.1161/01.HYP.0000084372.91932.BA.
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ET
A
Receptor Blockade Decreases Vascular Superoxide Generation in DOCA-Salt Hypertension
Glaucia E. Callera, Rhian M. Touyz, Simone A. Teixeira, Marcelo N. Muscara, Maria Helena C. Carvalho, Zuleica B. Fortes, Dorothy Nigro, Ernesto L. Schiffrin, and Rita C. Tostes
Hypertension. 2003;42:811-817; published online before print August 11 2003, doi:10.1161/01.HYP.0000088363.65943.6C.
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Elastase-Induced Suppression of Endothelin-Mediated Ca
2+
Entry Mechanisms of Vascular Contraction
David K.W. Chew, Julia M. Orshal, and Raouf A. Khalil
Hypertension. 2003;42:818-824; published online before print August 4 2003, doi:10.1161/01.HYP.0000086200.93184.8E.
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Endothelin-A Receptors Mediate Renal Hemodynamic Effects of Exogenous Angiotensin II in Humans
Alberto Montanari, Almerina Biggi, Nicoletta Carra, Maurizio Ziliotti, Elena Fasoli, Luisa Musiari, Patrizia Perinotto, and Almerico Novarini
Hypertension. 2003;42:825-830; published online before print August 18 2003, doi:10.1161/01.HYP.0000088361.26773.08.
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Interactions Between Vasoconstrictors and Vasodilators in Regulating Hemodynamics of Distinct Vascular Beds
Carlos Gomez-Alamillo, Luis A. Juncos, Aleix Cases, John A. Haas, and J. Carlos Romero
Hypertension. 2003;42:831-836; published online before print August 18 2003, doi:10.1161/01.HYP.0000088854.04562.DA.
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Role of COX-2 in the Enhanced Vasoconstrictor Effect of Arachidonic Acid in the Diabetic Rat Kidney
John Quilley and Yu-Jung Chen
Hypertension. 2003;42:837-843; published online before print August 4 2003, doi:10.1161/01.HYP.0000085650.29823.F2.
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PPAR
Inhibition of Cyclooxygenase-2, PGE
2
Synthase, and Inducible Nitric Oxide Synthase in Cardiac Myocytes
Mariela Mendez and Margot C. LaPointe
Hypertension. 2003;42:844-850; published online before print July 28 2003, doi:10.1161/01.HYP.0000085332.69777.D1.
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Training-Induced, Pressure-Lowering Effect in SHR: Wide Effects on Circulatory Profile of Exercised and Nonexercised Muscles
Ronaldo Meira Melo, Eduardo Martinho, Jr, and Lisete Compagno Michelini
Hypertension. 2003;42:851-857; published online before print August 11 2003, doi:10.1161/01.HYP.0000086201.27420.33.
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Role of Crk-Associated Substrate in the Regulation of Vascular Smooth Muscle Contraction
Dale D. Tang and Jian Tan
Hypertension. 2003;42:858-863; published online before print July 28 2003, doi:10.1161/01.HYP.0000085333.76141.33.
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