On the cover: Light micrographs of glomeruli of the kidneys of Sprague-Dawley rats administered saline vehicle (1 mL/h; n=6), angiotensin II (ANGII; 20 ng/kg per minute; n=7), or combined angiotensin II plus l-arginine (L-Arg; 300 µg/kg per minute; n=6) for 9 days. Glomerular sclerosis (blue fibrotic tissue and collapsed capillary structure) is present in the kidneys of rats administered angiotensin II. There is visibly less glomerular injury in rats coadministered l-arginine compared with rats administered angiotensin II alone. (See page 1086.)
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