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About This Cover
Volume 53, Issue 2; February 1, 2009
Editorial Commentaries
Original Articles
Letters to the Editor
Preface
Awards
Novartis Award for Hypertension Research
Lewis K. Dahl Memorial Lecture
Arthur C. Corcoran Memorial Lecture
Original Articles Part 2
Corrections
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Table of Contents (PDF)
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Editorial Commentaries
A Virtuous Cycle to Improve Hypertension Outcomes at a National Level: Linking Public Health and Individualized Medicine
Robert M. Califf
Hypertension. 2009;53:105-107; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.121608
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The Chicken and the Egg: Sympathetic Nervous System Activity and Left Ventricular Diastolic Dysfunction
Clive Rosendorff
Hypertension. 2009;53:108-109; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.126177
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Diabetes Mellitus and 24-Hour Ambulatory Blood Pressure Monitoring: Broadening Horizons of Risk Assessment
Michael Bursztyn and Iddo Z. Ben-Dov
Hypertension. 2009;53:110-111; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.119123
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Mitochondrial Dysfunction and Mitochondrial-Produced Reactive Oxygen Species: New Targets for Neurogenic Hypertension?
Matthew C. Zimmerman and Irving H. Zucker
Hypertension. 2009;53:112-114; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.125567
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A New Role for Caveolin-1: Regulation of Guanosine Triphosphate Cyclohydrolase I and Tetrahydrobiopterin in Endothelial Cells
Yan-Hua Du and Alex F. Chen
Hypertension. 2009;53:115-117; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.123356
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Sensing Salt Intake
Ines Armando and Pedro A. Jose
Hypertension. 2009;53:118-119; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.125310
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Original Articles
Ambulatory Blood Pressure Monitoring and All-Cause Mortality in Elderly People With Diabetes Mellitus
Walter Palmas, Thomas G. Pickering, Jeanne Teresi, Joseph E. Schwartz, Andrew Moran, Ruth S. Weinstock, and Steven Shea
Hypertension. 2009;53:120-127; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.118398
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Data Supplement
Increases in Antihypertensive Prescriptions and Reductions in Cardiovascular Events in Canada
Norm R.C. Campbell, Rollin Brant, Helen Johansen, Robin L. Walker, Andreas Wielgosz, Jay Onysko, Ru-Nie Gao, Christie Sambell, Stephen Phillips, Finlay A. McAlister for the Canadian Hypertension Education Program Outcomes Research Task Force
Hypertension. 2009;53:128-134; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.119784
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Pravastatin for Cardiovascular Event Primary Prevention in Patients With Mild-to-Moderate Hypertension in the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study
Toshio Kushiro, Kyoichi Mizuno, Noriaki Nakaya, Yasuo Ohashi, Naoko Tajima, Tamio Teramoto, Shinichiro Uchiyama, Haruo Nakamura for the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese Study Group
Hypertension. 2009;53:135-141; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.120584
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Evaluation of Noninvasive Methods to Assess Wave Reflection and Pulse Transit Time From the Pressure Waveform Alone
Jan G. Kips, Ernst R. Rietzschel, Marc L. De Buyzere, Berend E. Westerhof, Thierry C. Gillebert, Luc M. Van Bortel, and Patrick Segers
Hypertension. 2009;53:142-149; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.123109
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Data Supplement
Association Between C-Reactive Protein Genotype, Circulating Levels, and Aortic Pulse Wave Velocity
Wiebke Schumacher, John Cockcroft, Nicholas J. Timpson, Carmel M. McEniery, John Gallacher, Ann Rumley, Gordon Lowe, George Davey Smith, Ian B. Wilkinson, and Yoav Ben-Shlomo
Hypertension. 2009;53:150-157; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.117622
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Mineralocorticoid Receptor Antagonism Attenuates Vascular Apoptosis and Injury via Rescuing Protein Kinase B Activation
Yongzhong Wei, Adam T. Whaley-Connell, Javad Habibi, Jenna Rehmer, Nathan Rehmer, Kamlesh Patel, Melvin Hayden, Vincent DeMarco, Carlos M. Ferrario, Jamal A. Ibdah, and James R. Sowers
Hypertension. 2009;53:158-165; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.121954
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Data Supplement
Impaired Vasodilator Activity in Deoxycorticosterone Acetate-Salt Hypertension Is Associated With Increased Protein O-GlcNAcylation
Victor V. Lima, Fernanda R.C. Giachini, Hyehun Choi, Fernando S. Carneiro, Zidonia N. Carneiro, Zuleica B. Fortes, Maria Helena C. Carvalho, R. Clinton Webb, and Rita C. Tostes
Hypertension. 2009;53:166-174; published online before print January 12 2009, doi:10.1161/HYPERTENSIONAHA.108.116798
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Plasma Kallikrein Mediates Angiotensin II Type 1 Receptor–Stimulated Retinal Vascular Permeability
Joanna A. Phipps, Allen C. Clermont, Sukanto Sinha, Tamie J. Chilcote, Sven-Erik Bursell, and Edward P. Feener
Hypertension. 2009;53:175-181; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.117663
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Distinct Roles of Protease-Activated Receptors in Signal Transduction Regulation of Endothelial Nitric Oxide Synthase
Hiroyuki Suzuki, Evangeline D. Motley, Kunie Eguchi, Akinari Hinoki, Heigoro Shirai, Vabren Watts, Laura N. Stemmle, Timothy A. Fields, and Satoru Eguchi
Hypertension. 2009;53:182-188; published online before print December 8 2008, doi:10.1161/HYPERTENSIONAHA.108.125229
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Guanosine Triphosphate Cyclohydrolase I Expression and Enzymatic Activity Are Present in Caveolae of Endothelial Cells
Timothy E. Peterson, Livius V. d'Uscio, Sheng Cao, Xiao-Li Wang, and Zvonimir S. Katusic
Hypertension. 2009;53:189-195; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.115709
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Functional Characterization and Transcriptome Analysis of Embryonic Stem Cell–Derived Contractile Smooth Muscle Cells
Shiva Prasad Potta, Huamin Liang, Kurt Pfannkuche, Johannes Winkler, Shuhua Chen, Michael Xavier Doss, Kirsten Obernier, Naidu Kamisetti, Herbert Schulz, Norbert Hübner, Jürgen Hescheler, and Agapios Sachinidis
Hypertension. 2009;53:196-204; published online before print December 8 2008, doi:10.1161/HYPERTENSIONAHA.108.121863
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Sympathetic and Baroreflex Cardiovascular Control in Hypertension-Related Left Ventricular Dysfunction
Guido Grassi, Gino Seravalle, Fosca Quarti-Trevano, Raffaella Dell'Oro, Francesca Arenare, Domenico Spaziani, and Giuseppe Mancia
Hypertension. 2009;53:205-209; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.121467
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Angiotensin II Type 1 Receptor–Mediated Reduction of Angiotensin-Converting Enzyme 2 Activity in the Brain Impairs Baroreflex Function in Hypertensive Mice
Huijing Xia, Yumei Feng, Teresa D. Obr, Peter J. Hickman, and Eric Lazartigues
Hypertension. 2009;53:210-216; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.123844
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Oxidative Impairment of Mitochondrial Electron Transport Chain Complexes in Rostral Ventrolateral Medulla Contributes to Neurogenic Hypertension
Samuel H.H. Chan, Kay L.H. Wu, Alice Y.W. Chang, Ming-Hon Tai, and Julie Y.H. Chan
Hypertension. 2009;53:217-227; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.116905
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Salt Intake Augments Hypotensive Effects of Transient Receptor Potential Vanilloid 4: Functional Significance and Implication
Feng Gao, Dexin Sui, R. Michael Garavito, R. Mark Worden, and Donna H. Wang
Hypertension. 2009;53:228-235; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.117499
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Impact of Treatment on Myocardial Lysyl Oxidase Expression and Collagen Cross-Linking in Patients With Heart Failure
Begoña López, Ramón Querejeta, Arantxa González, Javier Beaumont, Mariano Larman, and Javier Díez
Hypertension. 2009;53:236-242; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.125278
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Transient Receptor Potential Vanilloid Gene Deletion Exacerbates Inflammation and Atypical Cardiac Remodeling After Myocardial Infarction
Wei Huang, Jack Rubinstein, Alejandro R. Prieto, Loc Vinh Thang, and Donna H. Wang
Hypertension. 2009;53:243-250; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.118349
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Sleep Modulates Hypertension in Leptin-Deficient Obese Mice
Alessandro Silvani, Stefano Bastianini, Chiara Berteotti, Carlo Franzini, Pierluigi Lenzi, Viviana Lo Martire, and Giovanna Zoccoli
Hypertension. 2009;53:251-255; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.125542
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Protective Role of Angiotensin II Subtype 2 Receptor in Blood Pressure Increase in Obese Zucker Rats
Athar H. Siddiqui, Quaisar Ali, and Tahir Hussain
Hypertension. 2009;53:256-261; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.126086
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Stress-Induced Sodium Excretion: A New Intermediate Phenotype to Study the Early Genetic Etiology of Hypertension?
Dongliang Ge, Shaoyong Su, Haidong Zhu, Yanbin Dong, Xiaoling Wang, Gregory A. Harshfield, Frank A. Treiber, and Harold Snieder
Hypertension. 2009;53:262-269; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.118117
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Increased Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Expression in the Maternal Vasculature of Women With Preeclampsia: Role for Peroxynitrite
Sowndramalingam Sankaralingam, Yi Xu, Tatsuya Sawamura, and Sandra T. Davidge
Hypertension. 2009;53:270-277; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.122630
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Letters to the Editor
Detection of Midpregnancy Fall in Blood Pressure by Out-of-Office Monitoring
Hirohito Metoki, Takayoshi Ohkubo, Yurie Sato, Maiko Kawaguchi, Misato Nishimura, Yumiko Watanabe, and Yutaka Imai
Hypertension. 2009;53:e12-e13; published online before print December 8 2008, doi:10.1161/HYPERTENSIONAHA.108.125294
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Response to Detection of Midpregnancy Fall in Blood Pressure by Out-of-Office Monitoring
Lindsay M. Silva, Eric A.P. Steegers, Alex Burdorf, Vincent W.V. Jaddoe, Lidia R. Arends, Albert Hofman, Johan P. Mackenbach, and Hein Raat
Hypertension. 2009;53:e14; published online before print December 8 2008, doi:10.1161/HYPERTENSIONAHA.108.125443
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Use of Protoporphyrins to Evaluate Heme Oxygenase Problematical
Robert S. Danziger
Hypertension. 2009;53:e15; published online before print December 1 2008, doi:10.1161/HYPERTENSIONAHA.108.125427
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Response to Use of Protoporphyrins to Evaluate Heme Oxygenase Problematical
Trinity Vera, Siliva Kelsen, and David E. Stec
Hypertension. 2009;53:e16; published online before print December 1 2008, doi:10.1161/HYPERTENSIONAHA.108.125583
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Aliskiren Therapy Will Have Minimal Effect on Intracellular Renin of Renin-Producing Cells
Duncan John Campbell
Hypertension. 2009;53:e17; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.126722
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Response to Aliskiren Therapy Will Have Minimal Effect on Intracellular Renin of Renin-Producing Cells
Manne Krop and A.H. Jan Danser
Hypertension. 2009;53:e18; published online before print January 5 2009, doi:10.1161/HYPERTENSIONAHA.108.126979
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Preface
The 62nd Annual Fall Conference and Scientific Session of the American Heart Association Council for High Blood Pressure Research in Association With the Council on the Kidney in Cardiovascular Disease
R. Clinton Webb
Hypertension. 2009;53:279-282, doi:10.1161/HYPERTENSIONAHA.109.000245
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Awards
Awards
Hypertension. 2009;53:283-285, doi:10.1161/HYPERTENSIONAHA.109.000264
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Novartis Award for Hypertension Research
Reconsidering the Roles of the Mineralocorticoid Receptor
John W. Funder
Hypertension. 2009;53:286-290; published online before print January 12 2009, doi:10.1161/HYPERTENSIONAHA.108.119966
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The Pump, the Exchanger, and Endogenous Ouabain: Signaling Mechanisms That Link Salt Retention to Hypertension
Mordecai P. Blaustein, Jin Zhang, Ling Chen, Hong Song, Hema Raina, Stephen P. Kinsey, Michelle Izuka, Takahiro Iwamoto, Michael I. Kotlikoff, Jerry B. Lingrel, Kenneth D. Philipson, W. Gil Wier, and John M. Hamlyn
Hypertension. 2009;53:291-298; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.119974
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Lewis K. Dahl Memorial Lecture
Mysteries of Renal Autoregulation
Edward W. Inscho
Hypertension. 2009;53:299-306; published online before print December 8 2008, doi:10.1161/HYPERTENSIONAHA.108.119982
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Arthur C. Corcoran Memorial Lecture
Sympathetic Activity, Vascular Capacitance, and Long-Term Regulation of Arterial Pressure
Gregory D. Fink
Hypertension. 2009;53:307-312; published online before print December 29 2008, doi:10.1161/HYPERTENSIONAHA.108.119990
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Original Articles Part 2
Angiotensin II Decreases Nitric Oxide Synthase 3 Expression via Nitric Oxide and Superoxide in the Thick Ascending Limb
Vanesa D. Ramseyer and Jeffrey L. Garvin
Hypertension. 2009;53:313-318; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.124107
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Possible Mediators of Connecting Tubule Glomerular Feedback
YiLin Ren, Martin A. D'Ambrosio, Jeffrey L. Garvin, Hong Wang, and Oscar A. Carretero
Hypertension. 2009;53:319-323; published online before print December 1 2008, doi:10.1161/HYPERTENSIONAHA.108.124545
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Contribution of Endothelin A Receptors in Endothelin 1–Dependent Natriuresis in Female Rats
Daisuke Nakano and David M. Pollock
Hypertension. 2009;53:324-330; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.123687
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Hypertension and Sex Differences in the Age-Related Renal Changes When Cyclooxygenase-2 Activity Is Reduced During Nephrogenesis
Fara Sáez, Virginia Reverte, Francisco Salazar, María T. Castells, María T. Llinás, and F. Javier Salazar
Hypertension. 2009;53:331-337; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.124354
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Intrarenal Angiotensin III Infusion Induces Natriuresis and Angiotensin Type 2 Receptor Translocation in Wistar-Kyoto but not in Spontaneously Hypertensive Rats
Shetal H. Padia, Brandon A. Kemp, Nancy L. Howell, John J. Gildea, Susanna R. Keller, and Robert M. Carey
Hypertension. 2009;53:338-343; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.124198
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Urinary Angiotensinogen as a Novel Biomarker of the Intrarenal Renin-Angiotensin System Status in Hypertensive Patients
Hiroyuki Kobori, A. Brent Alper, Jr, Rajesh Shenava, Akemi Katsurada, Toshie Saito, Naro Ohashi, Maki Urushihara, Kayoko Miyata, Ryousuke Satou, L. Lee Hamm, and L. Gabriel Navar
Hypertension. 2009;53:344-350; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.123802
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Angiotensin-Converting Enzyme–Derived Angiotensin II Formation During Angiotensin II–Induced Hypertension
Romer A. Gonzalez-Villalobos, Ryousuke Satou, Dale M. Seth, Laura C. Semprun-Prieto, Akemi Katsurada, Hiroyuki Kobori, and L. Gabriel Navar
Hypertension. 2009;53:351-355; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.124511
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Continuous Activation of Renin-Angiotensin System Impairs Cognitive Function in Renin/Angiotensinogen Transgenic Mice
Shinji Inaba, Masaru Iwai, Megumi Furuno, Yumiko Tomono, Harumi Kanno, Izumi Senba, Hideki Okayama, Masaki Mogi, Jitsuo Higaki, and Masatsugu Horiuchi
Hypertension. 2009;53:356-362; published online before print December 1 2008, doi:10.1161/HYPERTENSIONAHA.108.123612
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Nocturnal Blood Pressure Dipping in the Hypertension of Autonomic Failure
Luis E. Okamoto, Alfredo Gamboa, Cyndya Shibao, Bonnie K. Black, André Diedrich, Satish R. Raj, David Robertson, and Italo Biaggioni
Hypertension. 2009;53:363-369; published online before print December 1 2008, doi:10.1161/HYPERTENSIONAHA.108.124552
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Tonic Glutamatergic Input in the Rostral Ventrolateral Medulla Is Increased in Rats With Chronic Heart Failure
Wei-Zhong Wang, Lie Gao, Han-Jun Wang, Irving H. Zucker, and Wei Wang
Hypertension. 2009;53:370-374; published online before print November 24 2008, doi:10.1161/HYPERTENSIONAHA.108.122598
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Leptin Signaling in the Nucleus Tractus Solitarii Increases Sympathetic Nerve Activity to the Kidney
Allyn L. Mark, Khristofor Agassandian, Donald A. Morgan, Xuebo Liu, Martin D. Cassell, and Kamal Rahmouni
Hypertension. 2009;53:375-380; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.124255
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Obesity Increases Blood Pressure, Cerebral Vascular Remodeling, and Severity of Stroke in the Zucker Rat
Jessica M. Osmond, James D. Mintz, Brian Dalton, and David W. Stepp
Hypertension. 2009;53:381-386; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.124149
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Diabetic Hypertensive Leptin Receptor–Deficient db/db Mice Develop Cardioregulatory Autonomic Dysfunction
Andrey C. da Costa Goncalves, Jens Tank, André Diedrich, Aline Hilzendeger, Ralph Plehm, Michael Bader, Friedrich C. Luft, Jens Jordan, and Volkmar Gross
Hypertension. 2009;53:387-392; published online before print November 24 2008, doi:10.1161/HYPERTENSIONAHA.108.124776
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Prevalence of Agonistic Autoantibodies Against the Angiotensin II Type 1 Receptor and Soluble fms-Like Tyrosine Kinase 1 in a Gestational Age–Matched Case Study
Florian Herse, Stefan Verlohren, Katrin Wenzel, Juliane Pape, Dominik N. Muller, Susanne Modrow, Gerd Wallukat, Friedrich C. Luft, Christopher W.G. Redman, and Ralf Dechend
Hypertension. 2009;53:393-398; published online before print December 8 2008, doi:10.1161/HYPERTENSIONAHA.108.124115
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Hypertension Produced by Placental Ischemia in Pregnant Rats Is Associated With Increased Soluble Endoglin Expression
Jeffrey S. Gilbert, Sara A.B. Gilbert, Marietta Arany, and Joey P. Granger
Hypertension. 2009;53:399-403; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.123513
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Alterations in Circulatory and Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 in Fetal Programmed Hypertension
Hossam A. Shaltout, Jorge P. Figueroa, James C. Rose, Debra I. Diz, and Mark C. Chappell
Hypertension. 2009;53:404-408; published online before print December 1 2008, doi:10.1161/HYPERTENSIONAHA.108.124339
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Increased Activation of Stromal Interaction Molecule-1/Orai-1 in Aorta From Hypertensive Rats: A Novel Insight Into Vascular Dysfunction
Fernanda R.C. Giachini, Chin-Wei Chiao, Fernando S. Carneiro, Victor V. Lima, Zidonia N. Carneiro, Anne M. Dorrance, Rita C. Tostes, and R. Clinton Webb
Hypertension. 2009;53:409-416; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.124404
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Bradykinin Protects Against Oxidative Stress–Induced Endothelial Cell Senescence
Hisko Oeseburg, Dilek Iusuf, Pim van der Harst, Wiek H. van Gilst, Robert H. Henning, and Anton J.M. Roks
Hypertension. 2009;53:417-422; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.123729
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Dysregulation of Vascular TRPM7 and Annexin-1 Is Associated With Endothelial Dysfunction in Inherited Hypomagnesemia
Tamara M. Paravicini, Alvaro Yogi, Andrzej Mazur, and Rhian M. Touyz
Hypertension. 2009;53:423-429; published online before print December 22 2008, doi:10.1161/HYPERTENSIONAHA.108.124651
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Data Supplement
Which Sry Locus Is the Hypertensive Y Chromosome Locus?
Monte E. Turner, Joel Farkas, Jeff Dunmire, Daniel Ely, and Amy Milsted
Hypertension. 2009;53:430-435; published online before print December 15 2008, doi:10.1161/HYPERTENSIONAHA.108.124131
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Corrections
Corrections
Hypertension. 2009;53:e19, doi:10.1161/HYPERTENSIONAHA.109.000254
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Corrections
Hypertension. 2009;53:e20, doi:10.1161/HYPERTENSIONAHA.109.000255
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Corrections
Hypertension. 2009;53:e21, doi:10.1161/HYPERTENSIONAHA.109.000267
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