Table 2.

Baseline Ambulatory Blood Pressure Measurements and Least-Squares Mean Changes (Δ) From Baseline at Week 12

LisinoprilHCTZPlacebo
BP MeasurementsBaselineΔBaselineBaselineΔBaselineBaselineΔBaseline
Hours 0 to 24
SBP143.8−10.51146.3−12.41142.10.3
DBP88.5−7.2190.0−6.7188.30.7
Hours 1 to 12 (daytime)
SBP149.2−11.41150.2−11.81147.5−0.1
DBP92.7−7.6193.3−5.7193.10.5
Hours 13 to 24 (nighttime)
SBP138.2−9.61141.9−12.91136.20.6
DBP83.8−6.8186.1−7.7183.00.9
Hours 22 to 24 (trough)
SBP143.3−8.11147.9−14.11 2143.5−1.4
DBP90.5−7.1192.8−8.7190.5−0.7
  • BP values and changes are shown in mm Hg. At baseline, n=67 for lisinopril, n=64 for HCTZ, and n=65 for placebo.

  • 1 P<.05 active treatments vs placebo;

  • 2 P<.05 HCTZ vs lisinopril.