Table 6.

Cardiovascular Risk Factors in Adult Offspring Exposed to Maternal Hypertension in Pregnancy, and Offspring Born After Normotensive Pregnancy but Whose Mother Had At Least One Hypertensive Pregnancy

Risk FactorsBorn After Hypertensive PregnancyBorn After Normotensive Pregnancy, but With a Mother Who Had At Least One Hypertensive Pregnancy
Systolic blood pressure, mm Hg2.6 (1.7 to 3.5)2.8 (1.9 to 3.8)
Diastolic blood pressure, mm Hg1.5 (0.9 to 2.2)1.8 (1.0 to 2.5)
Body mass index, kg/m20.52 (0.18 to 0.86)0.49 (0.13 to 0.85)
Waist circumference, cm1.15 (0.26 to 2.04)1.44 (0.50 to 2.38)
Waist–hip ratio0.002 (−0.003 to 0.007)0.006 (0.001 to 0.011)
HDL cholesterol mmol/L−0.01 (−0.04 to 0.01)0.01 (−0.02 to 0.03)
Non-HDL cholesterol, mmol/L0.07 (0.00 to 0.14)−0.01 (−0.08 to 0.07)
Triglycerides, mmol/L0.03 (−0.02 to 0.08)0.01 (−0.04 to 0.07)
C-reactive protein, mg/L0.05 (−0.06 to 0.18)0.11 (−0.02 to 0.26)
  • Values are shown as mean differences (95 % CI) compared with offspring of women with no record of hypertensive pregnancy (adjusted for age, sex, maternal parity, and HUNT survey). The analysis includes 706 offspring born after hypertensive pregnancy, 653 offspring born after a normotensive pregnancy but whose mother has had at least 1 hypertensive pregnancy, and 14 419 offspring of mothers with no recorded hypertension in pregnancy. CI indicates confidence interval; HDL, high-density lipoprotein; and HUNT, Nord-Trøndelag Health Study.