Table 2.

Cardiovascular Risk Factors in Adult Offspring by Exposure to Any Maternal Hypertensive Disorder, Gestational Hypertension, or Preeclampsia

Mean Value (95% CI)Mean Differences (95% CI) From the No Hypertension Group
Hypertension status in uteroNo hypertensionAny hypertensionGestational hypertensionTerm PreeclampsiaPreterm Preeclampsia
No. of Participants15 07270633634327
No. of Observations18 73286441142231
Risk factors
 Systolic blood pressure, mm Hg123.0 (122.8–123.2)2.7 (1.8 to 3.5)3.3 (1.9 to 4.6)2.3 (1.1 to 3.5)−0.6 (−4.3 to 3.1)
 Diastolic blood pressure, mm Hg69.3 (69.1 to 69.4)1.5 (0.9 to 2.1)2.1 (1.2 to 3.0)1.0 (0.1 to 1.9)0.0 (−2.1 to 2.2)
 Body mass index, kg/m225.63 (25.56 to 25.70)0.66 (0.31 to 1.01)0.48 (0.00 to 0.97)0.93 (0.41 to 1.44)−0.78 (−2.05 to 0.49)
 Waist circumference, cm85.81 (85.63 to 85.99)1.49 (0.65 to 2.33)1.25 (0.10 to 2.41)1.86 (0.63 to 3.09)−0.50 (−4.74 to 3.75)
 Waist–hip ratio0.840 (0.839 to 0.841)0.003 (−0.002 to 0.008)0.000 (−0.006 to 0.006)0.006 (−0.001 to 0.013)0.007 (−0.018 to 0.031)
 HDL cholesterol, mmol/L1.33 (1.32 to 1.33)−0.02 (−0.04 to 0.01)−0.02 (−0.05 to 0.01)−0.01 (−0.05 to 0.02)−0.02 (−0.16 to 0.12)
 Non-HDL cholesterol, mmol/L3.56 (3.54 to 3.57)0.09 (0.01 to 0.16)0.03 (−0.07 to 0.13)0.14 (0.03 to 0.25)0.14 (−0.17 to 0.44)
 Triglycerides, mmol/L1.21 (1.20 to 1.22)0.05 (0.00 to 0.11)−0.03 (−0.09 to 0.05)0.13 (0.06 to 0.21)0.17 (−0.06 to 0.43)
 C-reactive protein, mg/L1.10 (1.06 to 1.14)0.05 (−0.06 to 0.18)0.08 (−0.09 to 0.28)0.01 (−0.14 to 0.18)0.38 (−0.18 to 1.28)
  • The values are shown as mean differences (95% CI) compared with offspring born after normotensive pregnancy (adjusted for age, sex, maternal parity, and HUNT survey [Nord-Trøndelag Health Study]). n=15 778 participants with 19 596 observations*. CI indicates confidence interval; and HDL, high-density lipoprotein.

  • *Number of observations for the different variables: systolic and diastolic blood pressure n=19 480, body mass index n=19 526, waist circumference n=19 234, waist–hip ratio n=19 232, HDL and non-HDL cholesterol n=19 159, triglycerides n=19 361, and C-reactive protein n=12 229.