Table 3.

HR for Severe Hypoglycemia in Type 2 Diabetes Mellitus Patients on β-Blockers Compared With Those Not on β-Blockers*

EventEvent Rate per Year (Events no./Total no.)HR (95% CI) for β (+) (vs β [−])P Value
β-blockers (−)β-blockers (+)
Severe hypoglycemia
 All1.1% (113/2527)1.5% (152/2527)1.36 (1.07–1.74)0.01
 Standard therapy0.7% (37/1273)0.7% (40/1273)1.10 (0.70–1.71)0.68
 Intensive therapy1.7% (83/1221)2.3% (112/1221)1.36 (1.03–1.81)0.03
  • β indicates β-blockers; CI, confidence interval; and HR, hazard ratio.

  • * Data are presented as number or HR (95% CI).