Table 2.

BP-Associated SNPs Associated With Expression of the Same Gene Across 4 or 3 Independent Whole-Blood eQTL Resources and the Kidney Resource

Sentinel SNPChrPositionGeneBlood Data SetsTop eQTLSignal in Other Tissue(s) in GTExSignal in KidneyeQTL Signal Previously Reported
Signal in 4 whole-blood eQTL resources
rs17367504111862778CLCN6YYYYYY
rs21691371204497913MDM4YYYYYYY
rs109269881243483279SDCCAG8YYYYY
rs319690347927484MAP4YYYYYYY
rs125218685131784393SLC22A5YYYYY
rs9001451113293905ARNTLYYYYYY
rs106010512123806219CDK2AP1YYYYYYY
rs13789421575077367SCAMP2YYYY
rs11264641689704365CHMP1AYYYYYY
rs11264641689704365FANCAYYYYY
rs129464541743208121DCAKDYYYYYYY
Signal in 3 (out of 4) whole-blood eQTL resources
rs17367504111862778MTHFRYYYNYY
rs871524138411445FHL3NYYYY
rs871524138411445SF3A3NYYYY
rs4660293140028180PABPC4YYYNYYY
rs67494472169041386STK39YYYNY
rs347591311290122ATG7YYYNY
rs319690347927484ZNF589YYNYY
rs125218685131784393SLC22A4YYYNY
rs1563788643308363CRIP3YYYNYY
rs10943605679655477PHIPYYYNYYY
rs47281427128573967IRF5NYYYYYY
rs47281427128573967TNPO3YYYNY
rs2898290811433909BLKYYYNY
rs2898290811433909FAM167ANYYYY
rs2898290811433909FDFT1YYYNY
rs20715188120435812NOVYYYNY
rs76452347935906471TPM2YYYN
rs107601179123586737MEGF9YYYNYY
rs44942501096563757HELLSYYYNY
rs1119154810104846178NT5C2YYYNY
rs661348111905292TNNT3NYYYY
rs2649044119763969SBF2YYYN
rs2649044119763969SWAP70YYYNYY?
rs71292201110350538ADMYYYNY
rs71036481147461783MYBPC3YYYN
rs37413781165408937CTSWYYYN
rs73029811250537815LIMA1YYYNY
rs73029811250537815ATF1YYNYY
rs10364771548914926FBN1YNYY
rs13789421575077367CSKYYYNYYY
rs13789421575077367MPINYYYY
rs13789421575077367ULK3YNYYYY
rs129464541743208121NMT1YYYNY
rs23041301919789528GATAD2AYYYN
rs8671862033764554EIF6NYYYY
rs60952412047308798PREX1YYYN
rs93061602145107562RRP1BYNYYYY
  • Signals of association of SNP genotype and gene expression in other nonblood tissues in GTEx and in kidney are also indicated. Blood data set order: (1) SABRe, (2) NESDA-NTR, (3) BIOS, and (4) GTEx (whole-blood). Top eQTL: top GWAS SNP is top eQTL SNP (or in high LD, r2>0.9, with top eQTL SNP) in at least 1 data set. eQTL signal previously reported: Genes for which eQTL signals have been previously reported for that sentinel SNP.15,16,18 For full list, see Table S12 in the online-only Data Supplement. eQTL indicates expression quantitative trait loci; GWAS, genome-wide association studies; GTEx, genotype-tissue expression; and LD, linkage disequilibrium; and SABRe, Systems Approach to Biomarker Research in Cardiovascular Disease.